Evidence map›Paper›PMID 41000217›Full record

ArticleFood technology and biotechnology

COX-2 Inhibition by Bioactive Peptides from Peanut Worm (

Suwarjoyowirayatno, Chusnul Hidayat, Tutik Dwi Wahyuningsih, Retno Indrati

Abstract read
In one paragraph

Article in Food technology and biotechnology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

SuwarjoyowirayatnoDepartment of Food and Agricultural Product Technology, Faculty of Agricultural Technology, Universitas Gadjah Mada, Flora Street, Bulaksumur, Yogyakarta 55281, Indonesia.ORCID https://orcid.org/0009-0000-7801-7978
Chusnul HidayatDepartment of Food and Agricultural Product Technology, Faculty of Agricultural Technology, Universitas Gadjah Mada, Flora Street, Bulaksumur, Yogyakarta 55281, Indonesia.ORCID https://orcid.org/0000-0001-6540-5306
Tutik Dwi WahyuningsihDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Gadjah Mada, Sekip Utara, Bulaksumur, Yogyakarta 55281, Indonesia.ORCID https://orcid.org/0000-0001-5741-2848
Retno IndratiDepartment of Food and Agricultural Product Technology, Faculty of Agricultural Technology, Universitas Gadjah Mada, Flora Street, Bulaksumur, Yogyakarta 55281, Indonesia.ORCID https://orcid.org/0000-0002-2809-5887

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Research background: Chronic, unregulated inflammation is a crucial factor in the development of numerous diseases and is closely linked to the increased expression of cyclooxygenase-2 (COX-2). While various bioactive peptides from marine organisms have shown COX-2 inhibitory effects, peptides derived from the collagen of the peanut worm ( Experimental approach: During simulated Results and conclusions: The 210-minute simulated digestion Novelty and scientific contribution: The study found that peptides derived from peanut worm collagen have the potential to be novel, natural agents for anti-inflammatory therapy. Their broader application in functional foods, nutraceuticals and pharmaceuticals could provide new options for people suffering from inflammation and support both treatment and maintenance of overall health.

Indexed as

bioactive peptideCOX-2 inhibitiondigestion simulationmolecular dockingpeanut worm collagenSiphonosoma australe

Identifiers

PMID41000217
PMCPMC12413490

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.