Evidence map›Paper›PMID 41000200›Full record

ArticleChemical & biomedical imaging2025

Quantifying the Shape and Stiffness of Single Extracellular Vesicles in Aqueous Solution via Membrane Diffusivity Measurements.

Yihan Wang, Huihui Gao, Chu Han, Liu Liu, Jingwen Deng, Hangwei Fan, Zirui Zhou, Mengyao Zhang, Xiaohui Zhang, Feiyang Cheng and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical & biomedical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Yihan WangCollege of Chemistry and Molecular Sciences & Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, Hubei 430072, China.
Huihui GaoCollege of Chemistry and Molecular Sciences & Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, Hubei 430072, China.ORCID https://orcid.org/0009-0000-2536-0852
Chu HanCollege of Chemistry and Molecular Sciences & Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, Hubei 430072, China.
Liu LiuCollege of Chemistry and Molecular Sciences & Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, Hubei 430072, China.
Jingwen DengCollege of Chemistry and Molecular Sciences & Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, Hubei 430072, China.
Hangwei FanCollege of Chemistry and Molecular Sciences & Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, Hubei 430072, China.
Zirui ZhouDepartment of Thyroid and Breast Surgery, Medical Research Institute, Frontier Science Center for Immunology and Metabolism, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, Hubei 430072, China.
Mengyao ZhangDepartment of Thyroid and Breast Surgery, Medical Research Institute, Frontier Science Center for Immunology and Metabolism, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, Hubei 430072, China.
Xiaohui ZhangCollege of Life Sciences & Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, Hubei 430072, China.
Feiyang ChengCollege of Chemistry and Molecular Sciences & Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, Hubei 430072, China.
Xiang ZhanDepartment of Biostatistics, Peking University, Beijing 100871, China.
Hao GeBeijing International Center for Mathematical Research (BICMR) and Biodynamic Optical Imaging Center (BIOPIC), Peking University, Beijing 100871, People's Republic of China.
Yan-Ling LiuCollege of Chemistry and Molecular Sciences & Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, Hubei 430072, China.ORCID https://orcid.org/0000-0002-7386-354X
Xinwei ZhangCollege of Chemistry and Molecular Sciences & Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, Hubei 430072, China.ORCID https://orcid.org/0000-0003-3325-5010
Wei-Hua HuangCollege of Chemistry and Molecular Sciences & Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, Hubei 430072, China.ORCID https://orcid.org/0000-0001-8951-075X
Wei YanCollege of Life Sciences & Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, Hubei 430072, China.ORCID https://orcid.org/0000-0003-3978-7675
Jing ZhangDepartment of Thyroid and Breast Surgery, Medical Research Institute, Frontier Science Center for Immunology and Metabolism, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, Hubei 430072, China.
Wei ZhangState Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, Department of Oral and Maxillofacial Surgery, School & Hospital of Stomatology, Wuhan University, Wuhan, Hubei 430079, China.
Limin XiangCollege of Chemistry and Molecular Sciences & Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, Hubei 430072, China.ORCID https://orcid.org/0000-0003-1488-2705

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quantifying the shape and stiffness of extracellular vesicles (EVs) is essential for understanding their biophysical properties and roles in intercellular communication. However, achieving single-particle resolution under physiological conditions remains a significant challenge. Here, we introduce an approach that integrates single-molecule diffusivity mapping (SM

Indexed as

DiffusionMembranesStiffnessSuper-resolution ImagingVesicles

Identifiers

PMID41000200
PMCPMC12458017

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.