Evidence map›Paper›PMID 41000183›Full record

ArticleFrontiers in pediatrics2025

Evaluation of a pediatric post-acute sequelae of SARS-CoV-2 index score.

Frederick Dun-Dery, Jianling Xie, Kathleen Winston, Brett Burstein, Vikram Sabhaney, Jason Emsley, Jocelyn Gravel, April Kam, Darcy Beer, Roger Zemek and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Frederick Dun-DeryDepartment of Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Jianling XieSection of Pediatric Emergency Medicine, Department of Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Kathleen WinstonDepartment of Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Brett BursteinDivision of Pediatric Emergency Medicine, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, Montreal, QC, Canada.
Vikram SabhaneyDepartment of Paediatrics, BC Children's Hospital and BC Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, Canada.
Jason EmsleyDepartment of Emergency Medicine, IWK Children's Health Centre and Queen Elizabeth II Health Sciences Centre, Dalhousie University, Halifax, NS, Canada.
Jocelyn GravelDepartment of Pediatric Emergency Medicine, Centre Hospitalier Universitaire (CHU) Sainte-Justine, Université de Montréal, Montreal, QC, Canada.
April KamDivision of Emergency Medicine, Department of Pediatrics, McMaster Children's Hospital, Hamilton, ON, Canada.
Darcy BeerDepartment of Pediatrics and Child Health, The Children's Hospital of Winnipeg, Children's Hospital Research Institute of Manitoba, University of Manitoba, Winnipeg, MB, Canada.
Roger ZemekDepartment of Pediatrics, University of Ottawa, Children's Hospital of Eastern Ontario, Ottawa, ON, Canada.
Ahmed MaterSection of Pediatric Emergency, Department of Pediatrics, Jim Pattison Children's Hospital, University of Saskatchewan, Saskatoon, SK, Canada.
Robert PorterJaneway Children's Health and Rehabilitation Centre, Newfoundland and Labrador Health Services, St John's, NL, Canada.
Gabrielle FreireDivision of Emergency Medicine, Department of Paediatrics, Hospital for Sick Children, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Naveen PoonaiDepartment of Paediatrics, Children's Hospital London Health Sciences Centre, Schulich School of Medicine & Dentistry, London, ON, Canada.
Simon BerthelotDépartement de Médecine Familiale et de Médecine d'Urgence, CHU de Québec-Université, Québec, QC, Canada.
Anne MoffattDepartment of Paediatrics, Kingston Health Sciences Centre, Queen's University, Kingston, ON, Canada.
Andrew DixonDepartment of Pediatrics, Stollery Children's Hospital, University of Alberta, Edmonton, AB, Canada.
Deepti ReddyClinical Research Unit, Children's Hospital of Eastern Ontario Research Institute, University of Ottawa, Ottawa, ON, Canada.
Marina SalvadoriPublic Health Agency of Canada, Ottawa, ON, Canada.
Stephen B FreedmanSections of Pediatric Emergency Medicine and Gastroenterology, Departments of Pediatrics and Emergency Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Pediatric Emergency Research Canada (PERC) COVID Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aims to assess the performance of the Researching COVID-19 to Enhance Recovery (RECOVER) initiative's proposed post-acute sequelae of COVID-19 (PASC) index in a cohort of children evaluated for SARS-CoV-2 infection, 6-12 months after exposure. Study design: We conducted a multicenter, prospective cohort study with 6- and 12-month follow-up in 14 Canadian tertiary-care pediatric emergency departments (EDs) in the Pediatric Emergency Research Canada network. Eligible children were 6 to <18 years of age who were tested for acute SARS-CoV-2 infection. We assessed the score validity and reliability and evaluated the associations between PASC index scores dichotomized using threshold values (≥5.5 for ages 6 to <12 years and ≥5.0 for ages 12 to <18 years) and SARS-CoV-2 infection. Results: Participants included 785 children, with a median age of 9 years (IQR: 7-13), enrolled between August 2020 and February 2022. Factor analysis identified characteristics that accounted for 32%-40% of variance. Strong correlations were identified between PASC index scores and PedsQL™ and overall health status; Cronbach's Conclusions: While scores correlated with quality of life and overall health, internal reliability was low to acceptable. The PASC index was not associated with previous SARS-CoV-2 infection.

Indexed as

emergency departmentindex scorepediatricpost-acute sequelae of SARS-CoV-2SARS-CoV-2

Identifiers

PMID41000183
PMCPMC12459272

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.