ArticleChemical science2025
Synthesis of biodegradable vinyl copolymers
Article in Chemical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Hydrogen Atom Transfer-Triggered Chemical Recycling of Commercial Poly(methyl methacrylate) Utilizing Continuous Monomer Removal.ACS macro letters · 2026Article
- Degradable Vinyl-Based Polymers by Radical Ring-Opening Polymerization: A User Guide.ACS polymers Au · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A method based on continuous Bayesian optimization of monomer feed in a semi-batch copolymerization is demonstrated that allows countering the composition drift in copolymerizations stemming from disparate reactivity ratios. The method requires online monitoring of the reaction, but requires no prior kinetic knowledge on the copolymerization or any modelling of the polymerizations, making this the first method generally applicable to any copolymerization system to achieve this aim. Copolymerizations between acrylates, methacrylates and styrene are demonstrated to achieve perfectly statistical and homogeneous distributions, and the radical ring opening copolymerisation between a cyclic ketene acetal and methyl methacrylate is showcased as an example of a challenging copolymerization where countering the composition drift results in a completely degradable material, paving a pathway to new sustainable polymers in the future. Next to perfect regulation of the sequence distribution in these copolymers, we also demonstrate how the method can be applied to create non-natural composition drifts in polymers at will.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.