Evidence map›Paper›PMID 40999982›Full record

ArticleInternational journal of oncology2025

ZBTB20 promotes ferroptosis through inhibiting TMEM109 expression in glioblastoma cells.

Xuhao Chen, Mingqi Luo, Xiaoyu Niu, Wang Wang, Huanhuan Cao, Liwei Zhang, Ruolun Wei, Ping Duan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xuhao ChenDepartment of Pathophysiology, College of Medicine, Zhengzhou University, Zhengzhou, Henan 450001, P.R. China.
Mingqi LuoDepartment of Pathophysiology, College of Medicine, Zhengzhou University, Zhengzhou, Henan 450001, P.R. China.
Xiaoyu NiuDepartment of Physiology and Neurobiology, College of Medicine, Zhengzhou University, Zhengzhou, Henan 450001, P.R. China.
Wang WangDepartment of Physiology and Neurobiology, College of Medicine, Zhengzhou University, Zhengzhou, Henan 450001, P.R. China.
Huanhuan CaoDepartment of Pathophysiology, College of Medicine, Zhengzhou University, Zhengzhou, Henan 450001, P.R. China.
Liwei ZhangDepartment of Physiology and Neurobiology, College of Medicine, Zhengzhou University, Zhengzhou, Henan 450001, P.R. China.
Ruolun WeiDepartment of Neurosurgery, Stanford University, Stanford, CA 94305, USA.
Ping DuanDepartment of Physiology and Neurobiology, College of Medicine, Zhengzhou University, Zhengzhou, Henan 450001, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ferroptosis is an iron‑dependent type of regulated cell death which is dysregulated in several tumors, including glioblastoma (GBM). Zinc finger and BTB domain‑containing protein 20 (

Indexed as

Brain NeoplasmsFerroptosisGlioblastomaMembrane ProteinsTranscription FactorsCell Line, TumorCell ProliferationGene Expression Regulation, NeoplasticGene Knockdown TechniquesHumansNerve Tissue ProteinsMembrane ProteinsNerve Tissue ProteinsTranscription FactorsZBTB20 protein, humanferroptosisgliomatransmembrane protein 109zinc finger and BTB domain‑containing protein 20

Identifiers

PMID40999982
PMCPMC12543314

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.