ArticleESC heart failure2025
Poor cardiovascular outcomes of underweight abdominal obesity in the entire population of newly diagnosed heart failure.
Article in ESC heart failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Associations of anthropometric-related phenotypes with functional and clinical outcomes in community-dwelling older adults: a cross-sectional analysis of ELSI-Brazil.BMC geriatrics · 2026Article
- Adipose Tissue, Natriuretic Peptides, and HFpEF: Clinical Implications of the Obesity Paradox.Biomedicines · 2026Review
- Nationwide Big Data Studies of Endocrine Diseases Using the Korean National Health Information Database: Research Trends and Standardization of Operational Definitions.Endocrinology and metabolism (Seoul, Korea) · 2026Review
- Poor cardiovascular outcomes of underweight abdominal obesity in the entire population of newly diagnosed heart failure.ESC heart failure · 2025Article
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9 authors.
Funding
Abstract
aimsBody mass index (BMI) has been widely used as a simple tool for predicting cardiovascular risk. Here we aimed to analyse the distribution and cardiovascular outcomes according to BMI and waist circumference (WC) of the newly diagnosed heart failure (HF) patients in the entire population of the Republic of Korea for 10 years.
methodsA total of 999 127 patients newly diagnosed with HF between 2012 and 2021 among the entire population were included. The epidemiologic data of each subgroup according to BMI and WC were analysed, and cardiovascular outcomes were evaluated.
resultsOver the decade from 2012 to 2021, the obese group accounted for 47.1% of the newly diagnosed HF population. Kaplan-Meier curve and hazard ratio of cardiovascular events in each subgroup revealed significantly increased rates of hospitalization, death from all causes, cardiovascular death, acute myocardial infarction, atrial fibrillation and composite cardiac events in the underweight group compared with other groups (P value < 0.05). The subgroups of abdominal obesity in normal, overweight and obese patients revealed significantly high hazard ratio in almost all cardiovascular events (P value < 0.05). Conversely, the overweight and obese groups without abdominal obesity showed the best cardiovascular outcomes. Increased cardiovascular risk was shown in groups with abdominal obesity even at the same BMI.
conclusionThe cardiovascular prognosis was significantly worse in the underweight group than in the obese group, especially in the underweight abdominal obesity group. Even in the same BMI group, the prognosis is worse in the group with abdominal obesity. For a more accurate cardiovascular prognosis analysis, it is necessary to use WC along with BMI.
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