Evidence map›Paper›PMID 40999862›Full record

ArticleAnnals of medicine2025

The positive correlation between the triglyceride glucose-body mass index and the presence and severity of early-onset coronary artery disease.

Ru-Hua Liu, Jing Li, Zhi-Xiang Sun, Ting-Ting Zhou, Cong Zhao, Qing-Wu Tian, Jun-Jie Guo, Chao Xuan

Abstract read
In one paragraph

Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ru-Hua LiuDepartment of Clinical Laboratory, The Affiliated Hospital of Qingdao University, Qingdao, China.
Jing LiDepartment of Clinical Laboratory, The Affiliated Hospital of Qingdao University, Qingdao, China.
Zhi-Xiang SunDepartment of Clinical Laboratory, Shinan District People's Hospital, Qingdao, China.
Ting-Ting ZhouDepartment of Clinical Laboratory, The Affiliated Hospital of Qingdao University, Qingdao, China.
Cong ZhaoDepartment of Cardiology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Qing-Wu TianDepartment of Clinical Laboratory, The Affiliated Hospital of Qingdao University, Qingdao, China.
Jun-Jie GuoDepartment of Cardiology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Chao XuanDepartment of Clinical Laboratory, The Affiliated Hospital of Qingdao University, Qingdao, China.ORCID 0000-0001-8273-0178

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe triglyceride glucose-body mass index (TyG-BMI) has emerged as a novel, comprehensive tool for evaluating insulin resistance and metabolic risk. We intend to determine the relationship between the TyG-BMI and early-onset coronary artery disease (CAD).

methodsA retrospective case-control study was performed, which included a cohort of 2,356 participants. Binary logistic regression was utilized to estimate odds ratios (ORs) and 95% confidence intervals (CIs), while restricted cubic splines (RCS) were applied to assess potential nonlinear associations. The predictive accuracy was evaluated using receiver operating characteristic (ROC) curves.

resultsThe TyG-BMI was significantly elevated and independently correlated with the presence of early-onset CAD (OR = 1.004, 95% CI: 1.002-1.007,

conclusionsThe TyG-BMI index is independently associated with the early-onset CAD and has demonstrated a significant correlation with the extent of coronary artery lesions. It may serve as a cost-effective and accessible tool for identifying individuals at higher risk.

Indexed as

Blood GlucoseBody Mass IndexCoronary Artery DiseaseTriglyceridesAdultAgedAge of OnsetCase-Control StudiesFemaleHumansInsulin ResistanceLogistic ModelsMaleMiddle AgedRetrospective StudiesRisk FactorsBlood GlucoseTriglyceridescoronary artery diseaseearly-onsetinsulin resistanceTyG-BMI

Identifiers

PMID40999862
PMCPMC12477769

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.