Evidence map›Paper›PMID 40999816›Full record

ReviewClinical transplantation and research2025

Deceased organ donation: laboratory testing and histocompatibility assessment in Korea.

Borae G Park, Samuel Lee

Abstract readReview
In one paragraph

Review in Clinical transplantation and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Borae G ParkKODA LAB, Korea Organ Donation Agency, Seoul, Korea.ORCID https://orcid.org/0000-0001-9710-9253
Samuel LeeKorea Organ Donation Agency, Seoul, Korea.ORCID https://orcid.org/0000-0002-5254-4048

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Histocompatibility testing is essential for ensuring both safety and fairness in deceased donor organ transplantation. In Korea, such testing is strictly regulated under the Organ Transplant Act and centralized within organ procurement organization laboratories. Standardized evaluations include ABO blood typing, infectious disease screening, human leukocyte antigen (HLA) typing, and crossmatching. Current allocation policies rely on low-resolution HLA typing and mandatory complement-dependent cytotoxicity crossmatch, with limited accommodations for highly sensitized patients; however, these measures remain inadequate to resolve prolonged waiting times and inequities. The integration of calculated panel-reactive antibody and virtual crossmatching provides opportunities to improve allocation fairness, reduce cold ischemic time, and minimize unnecessary crossmatches. This review outlines the Korean system of histocompatibility testing in deceased donor transplantation, highlights current challenges, and explores potential strategies for future improvement.

Indexed as

Deceased donor transplantationHistocompatibility testingHuman leukocyte antigenOrgan allocation

Identifiers

PMID40999816
PMCPMC12521843

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.