Evidence map›Paper›PMID 40999757›Full record

ArticleCell cycle (Georgetown, Tex.)

The GABBR1/miR-19b-3p/WNT2B axis regulates insulin resistance and liver injury in diabetes with viral infection: mechanistic and therapeutic insights.

Rui Yang, Jiangling Zhu, Lin Zou, Yingxuan Li, Li Peng, Xing Wang, Qian Xi, Fei Sun, Junhua Ma, Xia Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell cycle (Georgetown, Tex.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rui YangSchool of Gongli Hospital Medical Technology, University of Shanghai for Science and Technology, Shanghai, China.
Jiangling ZhuSchool of Gongli Hospital Medical Technology, University of Shanghai for Science and Technology, Shanghai, China.
Lin ZouDepartment of Endocrinology, Gongli Hospital of Shanghai Pudong New Area, Shanghai, China.
Yingxuan LiDepartment of Endocrinology, Gongli Hospital of Shanghai Pudong New Area, Shanghai, China.
Li PengDepartment of Endocrinology, Gongli Hospital of Shanghai Pudong New Area, Shanghai, China.
Xing WangDepartment of Endocrinology, Gongli Hospital of Shanghai Pudong New Area, Shanghai, China.
Qian XiDepartment of Endocrinology, Gongli Hospital of Shanghai Pudong New Area, Shanghai, China.
Fei SunDepartment of Endocrinology, Gongli Hospital of Shanghai Pudong New Area, Shanghai, China.
Junhua MaDepartment of Endocrinology, Gongli Hospital of Shanghai Pudong New Area, Shanghai, China.
Xia ChenSchool of Gongli Hospital Medical Technology, University of Shanghai for Science and Technology, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Insulin resistance (IR) is the main feature of type 2 diabetes mellitus. Furthermore, viral infection can aggravate the abnormal glucose metabolism in diabetic patients. GABBR1 can maintain normal glucose homeostasis, but its specific role in diabetes is not clear. We investigated the function of the GABBR1/miR-19b-3p/WNT2B axis

Indexed as

Diabetes Mellitus, ExperimentalDiabetes Mellitus, Type 2Insulin ResistanceLiverMicroRNAsWnt ProteinsAnimalsApoptosisCell LineHumansMaleMiceMice, Inbred C57BLPalmitic AcidSignal TransductionMicroRNAsMIRN19 microRNA, mousePalmitic AcidWnt ProteinsDiabetes mellitusGABBR1insulin resistanceliver injurymiR-19b-3p/WNT2B axisvirus infection

Identifiers

PMID40999757
PMCPMC12918276

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.