Evidence map›Paper›PMID 40999716›Full record

ArticleDevelopmental psychobiology2025

Social Smiling and Laughter Are Linked to Enhanced Functional Brain Connectivity in Young Infants' Default Mode Network.

Olivia Allison, Caroline Kelsey, Tobias Grossmann

Abstract read
In one paragraph

Article in Developmental psychobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Olivia AllisonDepartment of Psychology, University of Virginia, Charlottesville, Virginia, USA.
Caroline KelseyDepartment of Pediatrics, Division of Developmental Medicine, Boston Children's Hospital, Boston, Massachusetts, USA.
Tobias GrossmannDepartment of Psychology, University of Virginia, Charlottesville, Virginia, USA.

Funding

Neural Markers of Developmental Delays in Premature and Full Term InfantsK99HD115830 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI KELSEY, CAROLINE M. · 2024 to 2025
$265k
Danone North America, Gut Microbiome, Yogurt and Probiotics Fellowship grantEunice Kennedy Shriver National Institute of Child Health and Human DevelopmentNational Science FoundationNICHD NIH HHS K99 HD115830
6 · The paper itself

Abstract

The current study used functional near-infrared spectroscopy (fNIRS) to investigate whether and how individual differences in positive social engagement among 5-month-old (N = 109; N = 35 final sample) infants relate to variability in functional connectivity in the human brain's Default-Mode Network (DMN). Neuroimaging results showed that on average infants displayed greater functional connectivity in the right than in the left hemisphere of the DMN, adding to prior work indicating faster connectivity development in the right hemisphere. Results did not show any positive associations between our preregistered measures of positive social engagement and functional connectivity in the DMN. However, an additional analysis revealed that higher levels of infants' smiling and laughter during daily social interactions with their caregivers positively predicted DMN functional connectivity in the left hemisphere. This suggests that individual differences in connectivity in a long-range brain network implicated in a host of social and cognitive functions are associated with some aspects of infants' positive social-interactive behaviors.

Indexed as

BrainChild DevelopmentConnectomeDefault Mode NetworkInfant BehaviorLaughterNerve NetSmilingSocial InteractionFemaleFunctional NeuroimagingHumansIndividualityInfantMaleSpectroscopy, Near-InfraredfNIRSinfancymPFCpositive affectsocial behaviorSTC

Identifiers

PMID40999716
PMCPMC12464472

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.