Evidence map›Paper›PMID 40999616›Full record

ReviewAnti-cancer agents in medicinal chemistry2026

A Review of the Anticancer Properties of Cedrol and its Molecular Mechanisms.

Ali Mohammad Pourbagher-Shahri, Sajad Sahab-Negah, Meysam Moghbeli, Ehsan Saburi, Fatemeh Forouzanfar

Abstract readReview
PubMed Publisher
In one paragraph

Review in Anti-cancer agents in medicinal chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Overview of Research on Essential Oils ofPharmaceuticals (Basel, Switzerland) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ali Mohammad Pourbagher-ShahriNeuroscience Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Sajad Sahab-NegahNeuroscience Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Meysam MoghbeliMedical Genetics Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Ehsan SaburiMedical Genetics Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Fatemeh ForouzanfarNeuroscience Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite decades of research on promising new therapies, cancer remains a leading cause of morbidity and mortality. Over the years, extensive research has been conducted on the potential anticancer effects of various medicinal plants. One extremely promising agent or adjuvant that may be utilized for the prevention/ treatment of several malignancies is cedrol, a naturally occurring sesquiterpene. Cedrol modulates multiple molecular pathways involved in the protracted carcinogenesis process, including the generation of reactive oxygen species, activation of pro-death autophagy, inhibition of survival signals, promotion of apoptosis, and inhibition of minichromosome maintenance proteins. This review suggests that cedrol might be a unique medication for the treatment of glioblastoma, lung cancer, and colorectal cancers. Further in-depth investigations of cedrol's anticancer mechanisms are needed.

Indexed as

Antineoplastic AgentsAntineoplastic Agents, PhytogenicNeoplasmsPolycyclic SesquiterpenesAnimalsApoptosisAutophagyCell ProliferationHumansMolecular StructureReactive Oxygen SpeciesAntineoplastic AgentsAntineoplastic Agents, PhytogeniccedrolPolycyclic SesquiterpenesReactive Oxygen Speciesapoptosiscancercedrolmedicinal plantspro-death autophagySesquiterpene

Identifiers

PMID40999616

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.