Evidence map›Paper›PMID 40999519›Full record

ArticleTropical medicine and health2025

No evidence of Wuchereria bancrofti infection in Anopheles species after 10 years without mass drug administration: a molecular xenomonitoring study in Hauts-Bassins, Burkina Faso.

Achille Sindimbasba Nikièma, Lassane Koala, Rabila Bamogo, Simon P Sawadogo, Arielle Bettina Sandra Badiel, Ali Ouari, Abdoul-Aziz Millogo, Clarisse Bougouma, Mamadou Sermé, Soungalo Traoré and 2 more

Abstract read
In one paragraph

Article in Tropical medicine and health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Achille Sindimbasba NikièmaInstitut de Recherche en Sciences de la Santé, Direction Régionale de l'Ouest, Ministère de l'Enseignement Supérieur de la Recherche et de l'Innovation, Bobo-Dioulasso, Burkina Faso. achille.nikiema@yahoo.fr.
Lassane KoalaInstitut de Recherche en Sciences de la Santé, Direction Régionale de l'Ouest, Ministère de l'Enseignement Supérieur de la Recherche et de l'Innovation, Bobo-Dioulasso, Burkina Faso.
Rabila BamogoInstitut de Recherche en Sciences de la Santé, Direction Régionale de l'Ouest, Ministère de l'Enseignement Supérieur de la Recherche et de l'Innovation, Bobo-Dioulasso, Burkina Faso.
Simon P SawadogoInstitut de Recherche en Sciences de la Santé, Direction Régionale de l'Ouest, Ministère de l'Enseignement Supérieur de la Recherche et de l'Innovation, Bobo-Dioulasso, Burkina Faso.
Arielle Bettina Sandra BadielInstitut de Recherche en Sciences de la Santé, Direction Régionale de l'Ouest, Ministère de l'Enseignement Supérieur de la Recherche et de l'Innovation, Bobo-Dioulasso, Burkina Faso.
Ali OuariInstitut de Recherche en Sciences de la Santé, Direction Régionale de l'Ouest, Ministère de l'Enseignement Supérieur de la Recherche et de l'Innovation, Bobo-Dioulasso, Burkina Faso.
Abdoul-Aziz MillogoInstitut de Recherche en Sciences de la Santé, Direction Régionale de l'Ouest, Ministère de l'Enseignement Supérieur de la Recherche et de l'Innovation, Bobo-Dioulasso, Burkina Faso.
Clarisse BougoumaProgramme National de lutte contre les Maladies Tropicales Négligées, Ministère de la Santé, Ouagadougou, Burkina Faso.
Mamadou SerméProgramme National de lutte contre les Maladies Tropicales Négligées, Ministère de la Santé, Ouagadougou, Burkina Faso.
Soungalo TraoréProgramme National de lutte contre les Maladies Tropicales Négligées, Ministère de la Santé, Ouagadougou, Burkina Faso.
Babacar FayeUniversité Cheikh Anta Diop, Dakar, Sénégal.
Roch Kounbobr DabiréInstitut de Recherche en Sciences de la Santé, Direction Régionale de l'Ouest, Ministère de l'Enseignement Supérieur de la Recherche et de l'Innovation, Bobo-Dioulasso, Burkina Faso.

Funding

COR-NTD SGPV/0102/369
6 · The paper itself

Abstract

backgroundThe Lymphatic Filariasis Elimination Programme was launched in Burkina Faso in 2001 aiming to eliminate the disease as a public health concern through mass drug administration (MDA). After eight years of MDA, the Hauts-Bassins region successfully passed the Transmission Assessment Survey (TAS), which led to the MDA being stopped. This study aims to assess whether parasite transmission has resurfaced in areas where MDA was stopped more than ten years ago.

methodsA cross-sectional entomological survey was conducted in the villages of Tiebalogo and Tondogosso, in the Hauts-Bassins region. From August to December 2022, adult mosquitoes were collected using Human Landing Collection (HLC) indoor and outdoor, Window Exit Trap (WET) and Pyrethrum Spray Collection (PSC). Mosquitoes were identified morphologically. Genomic DNAs extracted from An. gambiae s.l., An. funestus, An. nili were amplified by PCR for Wuchereria bancrofti parasite detection.

resultsA total of 2688 mosquitoes were collected in both study sites, with 630 being collected in Tondogosso and 2058 in Tiebalogo. The An. gambiae s.l. was the predominant mosquitoes, with high numbers being collected in both sites. Of those collected in Tiebalogo, 1786 (86.78%) were identified as An. gambiae s.l., while 373 (59.21%) were identified in Tondogosso. The HLC method collected the greatest number of mosquitoes, followed by the PSC and WET methods. No Wuchereria bancrofti DNA was detected in any of the mosquito pools analyzed in both sites.

conclusionsThese findings provide further evidence that there is no Lymphatic Filariasis transmission occurring in Hauts-Bassin's post-TAS area. Molecular xenomonitoring of the filarial parasite which is a sensitive tool, could also serve as a complementary tool for monitoring transmission in post-MDA area and help national neglected tropical disease control program with surveillance in these areas.

Indexed as

An. funestusAn. gambiae s.l.An. niliBurkina FasoImplementation UnitLymphatic FilariasisMolecular XenomonitoringWuchereria bancrofti

Identifiers

PMID40999519
PMCPMC12465151

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.