Evidence map›Paper›PMID 40999507›Full record

ArticleTrials2025

Base curves of bandage contact lenses and their effects on post Trans-PRK vision and pain: the study protocol for a randomized clinical trial.

Gengmin Tong, Yuanhui Jin, Hangshuai Zhou, Yanhua Jin

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06393855 (Base Curves of Bandage Contact Lenses and Their Effects on Post Transepithelial Photorefractive Keratectomy), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06393855 naunknown statusnot on this map

Base Curves of Bandage Contact Lenses and Their Effects on Post Transepithelial Photorefractive Keratectomy (Trans-PRK) Vision and Pain: A Prospective Randomized Clinical Trial

TypeinterventionalSponsorDongyang People's HospitalRan2024 to 2025Enrolled36ConditionsMyopiaArmssingle-step Trans-PRK, Placing a bandage contact lens on the cornea, with an 8.4-mm base curve in right eye and one with an 8.8-mm base curve in the left eye., Placing a bandage contact lens on the cornea,A contact lens placed on the cornea, with an 8.8-mm base curve in right eye and one with an 8.4-mm base curve in the left eye.
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gengmin TongDongyang People's Hospital, Dongyang, 322100, China. fkstrer@163.com.ORCID http://orcid.org/0000-0002-3754-6491
Yuanhui JinDongyang People's Hospital, Dongyang, 322100, China.
Hangshuai ZhouDongyang People's Hospital, Dongyang, 322100, China.
Yanhua JinDongyang People's Hospital, Dongyang, 322100, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTransepithelial photorefractive keratectomy (Trans-PRK) is an effective and safe laser surgery for myopia. Following this procedure, a bandage contact lens is used to promote epithelial healing, reduce postoperative pain, and improve visual recovery. The base curve of these lenses may affect vision post-surgery, particularly in patients with steep corneas and high myopia. This study aims to investigate the impact of using bandage contact lenses with base curves of 8.4 mm versus 8.8 mm on visual recovery after Trans-PRK in patients with steep corneas and high myopia.

methodsThis is a randomized, double-blind, binocularly controlled, single-center trial. The study subjects are myopic patients scheduled for Trans-PRK. Both eyes in each patient will be treated consecutively with single-step Trans-PRK. After surgery, a contact lens with an 8.8-mm base curve will be placed on one eye, and a lens with an 8.4-mm base curve will be placed on the other. The primary objective is to determine the difference in early postoperative uncorrected visual acuity between the two eyes of patients with steep corneas and high myopia. Randomization will be conducted using a computer-generated random allocation sequence without blocks or restrictions. The sequence will be recorded in sealed opaque envelopes, maintained by the principal investigator until the trial's conclusion. In this double-masked trial, subjects will not know which treatment each eye receives. DISCUSSION: This novel trial will provide information on how bandage contact lenses with different base curves promote epithelial healing and visual recovery after Trans-PRK, thus offering evidence for clinical practice.

trial registrationClinicalTrials.gov NCT06393855. Registered on May 1, 2024. https://clinicaltrials.gov/study/NCT06393855 .

Indexed as

BandagesContact LensesCorneaMyopiaPhotorefractive KeratectomyPostoperative PainAdultDouble-Blind MethodEquipment DesignFemaleHumansMaleRandomized Controlled Trials as TopicTime FactorsTreatment OutcomeVision, Ocular

Identifiers

PMID40999507
PMCPMC12465201

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.