Evidence map›Paper›PMID 40999469›Full record

ArticleJournal of nanobiotechnology2025

Quadruple synergistic amplification of ferroptosis for precision glioblastoma therapy: a luteolin-coordinated ferric ion nanoplatform.

Suyi Liu, Kunhui Sun, Mengnan Li, Xinyue Liu, Ping Wang, Meifang Li, Bo Peng, Bing Wang, Yan-Xu Chang, Xie-An Yu

Abstract read
In one paragraph

Article in Journal of nanobiotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. The Therapeutic Potential of Dihydroartemisinin in Cancer Treatment.International journal of molecular sciences · 2026
    Review
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Suyi Liu *State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Kunhui Sun *State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Mengnan LiShenzhen Institute for Drug Control, Shenzhen, 518057, China.
Xinyue LiuShenzhen Institute for Drug Control, Shenzhen, 518057, China.
Ping WangShenzhen Institute for Drug Control, Shenzhen, 518057, China.
Meifang LiShenzhen Institute for Drug Control, Shenzhen, 518057, China.
Bo PengFrontiers Science Center for Flexible Electronics, Xi'an Institute of Flexible Electronics (IFE) and Xi'an Institute of Biomedical Materials & Engineering, Northwestern Polytechnical University, Xi'an, 710072, China. iambpeng@nwpu.edu.cn.
Bing WangShenzhen Institute for Drug Control, Shenzhen, 518057, China. wangbingszyj@163.com.
Yan-Xu ChangState Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China. Tcmcyx@tjutcm.edu.cn.
Xie-An YuShenzhen Institute for Drug Control, Shenzhen, 518057, China. yuxieanalj@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ferroptosis is emerging as a promising therapeutic strategy for glioblastoma (GBM). However, insufficient lipid peroxidation levels and blood-brain barrier (BBB) pose a significant challenge for GBM treatment. Here, we present natural product luteolin (Lut)-coordinated Fe

Indexed as

Brain NeoplasmsFerric CompoundsFerroptosisGlioblastomaLuteolinNanoparticlesAnimalsArtemisininsBlood-Brain BarrierCell Line, TumorHumansMiceMice, NudeArtemisininsartenimolFerric CompoundsLuteolinBlood-brain barrierFerroptosisGlioblastomaLuteolinMetal coordination

Identifiers

PMID40999469
PMCPMC12465256

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.