ArticleBMC surgery2025
Analysis of risk factors and clinical application of cardiovascular complications following lower limb joint replacement surgery in elderly patients.
Article in BMC surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- The blood glucose trajectories among non-diabetic patients with total joint arthroplasty: clinical characteristics and predictors.Frontiers in medicine · 2026Article
- To construct a risk prediction model for poor discharge readiness in patients undergoing elective unilateral lower extremity joint replacement based on clinical and psychosocial factors.Frontiers in medicine · 2026Article
- Noninvasive predictive value of preoperative perfusion index for intraoperative hemodynamic fluctuations in patients undergoing lower-extremity orthopedic surgery under regional anesthesia: a retrospective cohort study.Frontiers in surgery · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo identify the risk factors for cardiovascular complications following lower limb joint replacement surgery in elderly patients and to develop a risk assessment tool for clinical application to validate its efficacy.
methodsA retrospective analysis was conducted on 405 elderly patients (aged ≥ 65 years) who underwent lower limb joint replacement surgery at a hospital between January 2017 and December 2022. Statistically significant variables identified through univariate analysis were incorporated into a non-conditional binary logistic regression model for further analysis. The effectiveness of the logistic regression model was evaluated using the area under the receiver operating characteristic (ROC) curve (AUC). Based on the regression model, a risk assessment tool for cardiovascular complications post-surgery was established and clinically applied from February to July 2023 to determine criteria for identifying high-risk patients based on sensitivity and specificity.
resultsAmong the 405 patients in the retrospective study, 32 (7.90%) experienced cardiovascular complications postoperatively. Logistic regression analysis indicated that age (OR 1.98, 95% CI 1.15-3.43), body mass index (BMI) (OR 2.80, 95% CI 1.28-6.16), preoperative lipoprotein (a) (OR 1.97, 95% CI 0.90-4.35), ASA classification (OR 3.57, 95% CI 1.14-11.18), and anesthesia method (OR 0.36, 95% CI 0.18-0.71) were independent risk factors for cardiovascular complications in this population (P < 0.05). The AUC was 0.773, with a 95% confidence interval of (0.684-0.861). In the clinical application of the risk assessment tool, 5 out of 83 patients (6.02%) developed cardiovascular complications post-surgery, indicating that patients with preoperative scores exceeding 6.5 and total postoperative scores exceeding 8.5 had a significantly higher risk of complications.
conclusionThis preliminary study elucidated the risk factors for cardiovascular complications following lower limb joint replacement surgery in elderly patients and established a risk assessment tool that demonstrated promising results in initial clinical application. Further validation in larger, multi-center studies is needed before widespread implementation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.