Evidence map›Paper›PMID 40999400›Full record

ReviewBiotechnology for biofuels and bioproducts2025

Advances in the sustainable biosynthesis of valuable terpenoid flavor compounds and precursors in micro-organisms.

Qian Li, Yibo Ning, Deyu Liu, Jie Ren, Changtong Lu, Zhifei Chen, Guanglu Wang

Abstract readReview
In one paragraph

Review in Biotechnology for biofuels and bioproducts, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Terpenoids fromPlants (Basel, Switzerland) · 2026
    Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qian LiCollege of Tobacco Science and Engineering, Zhengzhou University of Light Industry, No.136 Ke Xue Avenue, Zhengzhou, 450001, Henan, China.
Yibo NingTechnology Center, China Tobacco Henan Industrial Co., Ltd, Zhengzhou, 450002, China.
Deyu LiuCollege of Tobacco Science and Engineering, Zhengzhou University of Light Industry, No.136 Ke Xue Avenue, Zhengzhou, 450001, Henan, China.
Jie RenCollege of Tobacco Science and Engineering, Zhengzhou University of Light Industry, No.136 Ke Xue Avenue, Zhengzhou, 450001, Henan, China.
Changtong LuTechnology Center, China Tobacco Henan Industrial Co., Ltd, Zhengzhou, 450002, China.
Zhifei ChenTechnology Center, China Tobacco Henan Industrial Co., Ltd, Zhengzhou, 450002, China. chenzhifei@126.com.
Guanglu WangCollege of Tobacco Science and Engineering, Zhengzhou University of Light Industry, No.136 Ke Xue Avenue, Zhengzhou, 450001, Henan, China. wangguanglu@zzuli.edu.cn.

Funding

Technical Program of China Tobacco Henan Industrial AW2024005
6 · The paper itself

Abstract

Renowned for their distinctive aromas, terpenoid flavor compounds and their precursors are widely used in medicine, food, and the flavor and fragrance industries. Rapid advances in synthetic biology, including the modification of microbial chassis cells, the design of synthetic pathways for novel target products, and the integration of large-scale microbial fermentation, have enabled the development of microbial cell factories for the green and efficient production of terpenoid flavor compounds and their precursors, offering broader market potential. This review examines common biosynthetic mechanisms, recent progress in the field, and strategies for enhancing the biosynthetic efficiency of terpenoid flavor compounds and their precursors. This study aims to support the advancements of sustainable production technologies and promote industrial application within the flavor and fragrance sector.

Indexed as

Biosynthetic strategyFlavors and fragrancesMicrobial cell factoryTerpenoids

Identifiers

PMID40999400
PMCPMC12465583

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.