Evidence map›Paper›PMID 40999280›Full record

ArticlePhotochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology2025

Effect of photobiomodulation therapy on surfactant production increase in human lung epithelial alveolar cells.

Halil İbrahim Özdemir, Metin Bilge, Ertuğrul Özkan, Nur Selvi Günel, Hatice Elif Özdemir, Ayshan Ahadova, Ayşe Çekin, Latife Merve Oktay Çelebi, Çağla Kayabaşı, Züleyha Özçelik Çetinel and 11 more

Abstract read
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In one paragraph

Article in Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Halil İbrahim ÖzdemirDepartment of Radiodiagnostics, Faculty of Medicine, Ege University, İzmir, Turkey.
Metin BilgeDepartment of Physics, Faculty of Science, Ege University, İzmir, Turkey.
Ertuğrul ÖzkanDepartment of Physics, Faculty of Science, Ege University, İzmir, Turkey.
Nur Selvi GünelDepartment of Medical Biology, Faculty of Medicine, Ege University, İzmir, Turkey. selvi.nur@gmail.com.
Hatice Elif ÖzdemirDepartment of Norology, Faculty of Medicine, Manisa Celal Bayar University, Manisa, Turkey.
Ayshan AhadovaDepartment of Medical Biology, Faculty of Medicine, Ege University, İzmir, Turkey.
Ayşe ÇekinDepartment of Medical Biology, Faculty of Medicine, Ege University, İzmir, Turkey.
Latife Merve Oktay ÇelebiDepartment of Medical Biology, Faculty of Medicine, Ege University, İzmir, Turkey.
Çağla KayabaşıDepartment of Medical Biology, Faculty of Medicine, Balıkesir University, Balıkesir, Turkey.
Züleyha Özçelik ÇetinelDepartment of Physics, Faculty of Science, Ege University, İzmir, Turkey.
Duygu BilgeDepartment of Physics, Faculty of Science, Ege University, İzmir, Turkey.
Murat KoyluDepartment of Radiation Oncology, Faculty of Medicine, Ege University, İzmir, Turkey.
Cansın Şirin TomrukDepartment of Histology and Embryology, Faculty of Medicine, Ege University, İzmir, Turkey.
Canberk TomrukDepartment of Histology and Embryology, Faculty of Medicine, Ege University, İzmir, Turkey.
Şenay ŞanlıerDepartment of Biochemistry, Faculty of Science, Ege University, İzmir, Turkey.
Demet TerekDepartment of Child Health and Diseases, Faculty of Medicine, Ege University, İzmir, Turkey.
Elif ErolClinical Research Associate, IQVIA, Istanbul, Turkey.
Fahri Emrah SoyluEGEHAYMER, Ege University, İzmir, Turkey.
Mehmet YalazDepartment of Child Health and Diseases, Faculty of Medicine, Ege University, İzmir, Turkey.
İsmail OranDepartment of Radiodiagnostics, Faculty of Medicine, Ege University, İzmir, Turkey.
Cumhur GündüzDepartment of Medical Biology, Faculty of Medicine, Ege University, İzmir, Turkey.

Funding

Türkiye Bilimsel ve Teknolojik Araştırma Kurumu SBAG 221S431
6 · The paper itself

Abstract

This study aimed to investigate photobiomodulation (PBM) by infrared LED lights as a non-invasive treatment for respiratory distress syndrome in premature and mature newborns, utilizing mature human lung epithelial alveolar cells as a model system. Human lung epithelial alveolar cells were irradiated using liquid-cooled infrared LED setups. Experiments were conducted with three wavelengths (660, 830, 940 nm), two light powers (30, 60 mW), and four energy levels (3, 5, 10, 15 J/cm

Indexed as

Alveolar Epithelial CellsLow-Level Light TherapyPulmonary Surfactant-Associated ProteinsPulmonary SurfactantsCells, CulturedHumansInfrared RaysLungPulmonary Surfactant-Associated ProteinsPulmonary SurfactantsAlveolar surfactantIR LED/laser therapyLung epithelial alveolar cellsPhotobiomodulation therapyPrematureRespiratory distress syndrome

Identifiers

PMID40999280

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.