Evidence map›Paper›PMID 40999222›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Association of spino-pelvic sagittal parameters with pain and disability outcomes following lumbar fusion: a prospective cohort study.

Zahra Sheidae Mehne, Farhad Motlagh Pirooz

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Zahra Sheidae MehneMashhad University of Medical Sciences, Mashhad, Iran. sheidae.zahra@yahoo.com.
Farhad Motlagh PiroozMashhad University of Medical Sciences, Mashhad, Iran. motlagh41@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSagittal alignment restoration is considered crucial for successful lumbar fusion outcomes, yet the specific relationships between spino-pelvic parameters and patient-reported outcomes remain incompletely understood. This prospective cohort study investigated associations between sagittal alignment parameters and pain/disability outcomes following lumbar fusion surgery.

methodsFifty-nine patients with lumbar spondylolisthesis undergoing short-segment transforaminal lumbar interbody fusion (TLIF) were prospectively enrolled. Radiographic parameters including pelvic incidence (PI), pelvic tilt (PT), sacral slope (SS), lumbar lordosis (LL), thoracic kyphosis (TK), and sagittal vertical axis (SVA) were measured pre- and post-operatively. Visual analog scale (VAS) and Oswestry Disability Index (ODI) were assessed pre-operatively and at final follow-up (median 99.5 days). Correlational analyses correlated sagittal parameters, parameter changes, and clinical outcomes.

resultsDespite substantial clinical improvement (median ODI: 72 to 15, p < 0.001; mean VAS: 8.95 to 2.55, p < 0.001), average lumbar lordosis decreased by 4.1°, and SVA increased by 18.5 mm postoperatively. Of all radiographic parameters analyzed, only the change in lumbar lordosis (ΔLL) was significantly associated with pain improvement (ΔVAS, r = - 0.288, p = 0.027). Changes in other parameters, including SVA, and absolute postoperative alignment values, were not significantly associated with clinical outcomes.

conclusionsIn this cohort, revealed a clinical-radiographic paradox where patients experienced substantial symptom relief after fusion despite a lack of overall sagittal alignment correction. Early pain improvement correlated only with the magnitude of individualized lordosis restoration, not with achieving normative targets. These findings suggest surgical strategy should prioritize patient-specific realignment over the pursuit of universal radiographic goals.

Indexed as

Lumbar VertebraePelvisSpinal FusionSpondylolisthesisAdultAgedDisability EvaluationFemaleHumansLordosisMaleMiddle AgedPain MeasurementProspective StudiesTreatment OutcomeDegenerative disc diseaseLumbar fusionLumbar lordosisPatient-reported outcomesSagittal alignmentSpinopelvic parameters

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.