Evidence map›Paper›PMID 40999202›Full record

ArticleNeuroradiology2025

Quantitative digital subtraction angiography analysis and predictive factors for incomplete occlusion in posterior communicating artery aneurysms after endovascular treatment.

Sheng-Qi Hu, Chun Zeng, Jinbiao Yao, Mirzat Turhon, Ting Liu, Wenqiang Li, Xinjian Yang

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Article in Neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 citing paper in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Sheng-Qi Hu *Beijing Neurosurgical Institute, Capital Medical University, Beijing, China. hsqhuaqi@163.com.
Chun Zeng *Beijing TianTan Hospital, Capital Medical University, Beijing, China.
Jinbiao Yao *Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Mirzat TurhonBeijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Ting LiuBeijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Wenqiang LiBeijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Xinjian YangBeijing Neurosurgical Institute, Capital Medical University, Beijing, China. yangxinjian@voiceoftiantan.org.

Funding

China Postdoctoral Science Foundation 2024M75178National Natural Science Foundation of China 82372058Postdoctoral Fellowship Program of CPSF GZC20241099
6 · The paper itself

Abstract

purposeThis study aimed to identify predictive factors for incomplete occlusion in posterior communicating artery (PCoA) aneurysms after endovascular treatment (EVT) and investigate the role of fetal-type posterior cerebral artery (fPCA) in occlusion outcomes using quantitative digital subtraction angiography (QDSA).

methodsWe analyzed 287 patients with 292 PCoA aneurysms treated with EVT between 2016 and 2022. Aneurysms were categorized into incomplete (n = 49) and complete (n = 243) occlusion groups based on follow-up DSA. Clinical, morphological, and hemodynamic parameters from QDSA were compared, and independent risk factors were identified via multivariate logistic regression. Predictive performance was evaluated using area under the curve (AUC) and subgroup analysis with Benjamini-Hochberg correction for fPCA effects.

resultsIndependent risk factors for incomplete occlusion included size (p < 0.001, OR = 1.127), neck cerebral blood flow (CBF) (p = 0.001, OR = 4.024), simple coiling (p < 0.001, OR = 4.635), ruptured status (p = 0.002, OR = 3.281), and fPCA (p = 0.030, OR = 2.218). AUCs for the combined model, size, neck CBF, simple coiling, ruptured status, and fPCA were 0.822, 0.721, 0.708, 0.656, and 0.603, respectively. In the fPCA subgroup, ruptured status, neck CBF, neck cerebral blood volume (CBV), PCoA CBF, and PCoA CBV showed significance, while in the non-fPCA subgroup, only simple coiling and size remained significant.

conclusionSize, neck CBF, simple coiling, ruptured status, and fPCA are independent risk factors for incomplete occlusion in PCoA aneurysms treated with EVT. fPCA likely influences incomplete occlusion through hemodynamic changes.

Indexed as

Angiography, Digital SubtractionCerebral AngiographyEndovascular ProceduresIntracranial AneurysmAgedFemaleHumansMaleMiddle AgedPredictive Value of TestsRetrospective StudiesRisk FactorsTreatment OutcomeFetal-type posterior cerebral arteryIncomplete occlusionMorphologyPosterior communicating artery aneurysmQuantitative digital subtraction angiography

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.