Evidence map›Paper›PMID 40999113›Full record

ArticleAnnals of intensive care2025

Impact of early PaCO

Xiaoli Chen, Jinquan Xie, Ya Wang, Zhongtao Du, Xinyi Luo, Zitao Zeng, Haixiu Xie, Jinxiang Ma, Zhangwei Liang, Yin Xi and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of intensive care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Xiaoli Chen *Department of Critical Care Medicine, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory and Health, Medical Center for Respiratory Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Jinquan Xie *Department of Critical Care Medicine, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory and Health, Medical Center for Respiratory Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Ya Wang *Department of Critical Care Medicine, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory and Health, Medical Center for Respiratory Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Zhongtao Du *Center for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Xinyi Luo *Department of Critical Care Medicine, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory and Health, Medical Center for Respiratory Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Zitao ZengDepartment of Critical Care Medicine, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Haixiu XieCenter for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Jinxiang MaDepartment of Statistics, Guangzhou Medical University, Guangzhou, China.
Zhangwei LiangDepartment of Critical Care Medicine, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory and Health, Medical Center for Respiratory Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Yin XiDepartment of Critical Care Medicine, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory and Health, Medical Center for Respiratory Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Jie ZhangDepartment of Critical Care Medicine, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory and Health, Medical Center for Respiratory Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Weibo LiangDepartment of Critical Care Medicine, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory and Health, Medical Center for Respiratory Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Chenglong LiCenter for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Zhenting LiangDepartment of Critical Care Medicine, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory and Health, Medical Center for Respiratory Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Jiao LiDepartment of Critical Care Medicine, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory and Health, Medical Center for Respiratory Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Weiqun HeDepartment of Critical Care Medicine, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory and Health, Medical Center for Respiratory Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Xiaoqing LiuDepartment of Critical Care Medicine, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory and Health, Medical Center for Respiratory Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Yimin LiDepartment of Critical Care Medicine, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory and Health, Medical Center for Respiratory Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. dryiminli@vip.163.com.
Xiaotong HouCenter for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical University, Beijing, China. xt.hou@ccmu.edu.cn.
Yonghao XuDepartment of Critical Care Medicine, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory and Health, Medical Center for Respiratory Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. dryonghao@163.com.ORCID http://orcid.org/0000-0002-4905-0979

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeurological complications significantly contributed to mortality in patients with acute respiratory distress syndrome (ARDS) supported by venovenous extracorporeal membrane oxygenation (VV ECMO). Early fluctuations in arterial partial pressure of carbon dioxide (PaCO

methodsWe conducted a retrospective cohort study using data from adult ARDS patients who underwent VV ECMO between January 2018 and December 2022, sourced from the Chinese Society of Extracorporeal Life Support (CSECLS) Registry. Patients were stratified into clusters based on absolute changes in PaCO

resultsAmong 983 patients included, the incidence of neurological complications was 2.95%. Cluster 1, characterized by significant reductions in PaCO

conclusionsExcessive reductions in PaCO

Indexed as

Acute respiratory distress syndromeArterial partial pressure of carbon dioxideNeurological complicationsVenovenous extracorporeal membrane oxygenation

Identifiers

PMID40999113
PMCPMC12463811

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.