Evidence map›Paper›PMID 40998956›Full record

ArticleScientific reports2025

A nationwide comparative study of pediatric and adult intussusception in emergency departments during the COVID-19.

Dong-Uk Kim, Hyerin Gim, Eun Hee Chung

Abstract readComparative Study
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Malignancy risk and management outcomes in adult intussusception: a single-institution retrospective study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dong-Uk Kim *Department of Pediatrics, Seoul National University College of Medicine, Seoul, South Korea.
Hyerin Gim *Infectious Disease Control Division, Seoul Metropolitan Government, Citizens' Health Bureau, Seoul, South Korea.
Eun Hee ChungDepartment of Pediatrics, Chungnam National University School of Medicine, Daejeon, South Korea. ehchung@cnu.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intussusception is a common cause of acute abdominal pain among children presenting to emergency departments, but it is rare in adults, with distinct clinical and epidemiological patterns. However, large-scale comparative data are scarce, and the impact of infectious disease remains poorly understood. We analyzed nationwide emergency department data from South Korea (2019-2023) to compare cross-age clinical characteristics and investigate temporal trends associated with infectious disease incidence, using COVID-19 social distancing as a natural experiment. Among 14,723 cases, 80.8% were pediatric patients, peaking at ages 1-4, while adult cases were evenly distributed. Children presented to higher-level centers, whereas adults required hospitalization with higher clinical acuity. Vomiting and hematochezia predominated in pediatric patients, while abdominal pain and nonspecific symptoms like asthenia and dyspnea were more common in adults. During COVID-19 distancing, pediatric intussusception declined significantly, while adult cases remained stable. Correlation analysis revealed stronger associations of pediatric intussusception with respiratory viruses, particularly adenovirus and rhinovirus, than with enteric pathogens. Causal mediation analysis confirmed that respiratory viruses accounted for 65.6% of the pandemic-associated reduction, with adenovirus (68.3%) and rhinovirus (62.8%) contributing most. These findings highlight age-dependent differences and suggest temporal associations between respiratory viral infections and pediatric intussusception.

Indexed as

COVID-19Emergency Service, HospitalIntussusceptionAbdominal PainAdolescentAdultAgedChildChild, PreschoolFemaleHospitalizationHumansIncidenceInfantMaleMiddle AgedCOVID-19Emergency medical servicesEnteric pathogenIntussusceptionPediatricRespiratory virus

Identifiers

PMID40998956
PMCPMC12464238

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.