Evidence map›Paper›PMID 40998950›Full record

ArticleBritish journal of cancer2025

Ethnic disparities in opioid prescribing for cancer pain and associated emergency department visits and hospital admissions in the last three months of life: a retrospective cohort study.

Emeka Chukwusa, Sophie Law-Clucas, Martin Gulliford, Sabrina Bajwah, Stephen Barclay, Rashmi Kumar, Gemma Clarke, Tanya Siriwimala, Jonathan Koffman

Abstract read
In one paragraph

Article in British journal of cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Cancer pain.Nature reviews. Disease primers · 2026
    Review
  2. Review
  3. Article
  4. Key issues in palliative and supportive care research, policy and practice.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Emeka ChukwusaInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.
Sophie Law-ClucasWolfson Palliative Care Research Centre, Hull York Medical School, University of Hull, Hull, United Kingdom.
Martin GullifordSchool of Population Health and Environmental Sciences, King's College London, London, United Kingdom.ORCID http://orcid.org/0000-0003-1898-9075
Sabrina BajwahCicely Saunders Institute, King's College London, London, United Kingdom.
Stephen BarclayDepartment of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
Rashmi KumarCicely Saunders Institute, King's College London, London, United Kingdom.
Gemma ClarkeAcademic Unit of Palliative Care, Leeds Institute of Health Sciences, University of Leeds, Leeds, United Kingdom.
Tanya SiriwimalaGuy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Jonathan KoffmanWolfson Palliative Care Research Centre, Hull York Medical School, University of Hull, Hull, United Kingdom. Jonathan.koffman@hyms.ac.uk.ORCID http://orcid.org/0000-0001-8513-5681

Funding

DH | NIHR | Research for Patient Benefit Programme (NIHR Research for Patient Benefit Programme) NIHR202726
6 · The paper itself

Abstract

backgroundEthnic inequalities in pain management at the end of life remain underexplored in the UK. We examined associations between patient ethnicity, opioid prescribing, and related healthcare use among cancer decedents.

methodsRetrospective cohort study including 232,329 adults (≥18 years) diagnosed with cancer between 2011 and 2021. Primary care records from the Clinical Practice Research Datalink Aurum were linked to hospital and mortality data. Person-time rates of opioid prescriptions, emergency department (ED) visits, and hospital admissions in the last three months of life were estimated. Poisson regression with Generalised Estimating Equations generated adjusted rate ratios (aRRs) and 95% confidence intervals (CIs), controlling for relevant covariates.

resultsOf 3,987,635 opioid prescriptions, 620,232 (16%) occurred in the final three months. Prescription rates were highest among White patients (969.97-894.43/1000 person-months). Compared with White patients, prescribing was significantly lower among Black (aRR 0.91, 95% CI 0.87-0.95), South Asian (aRR0.93, CI0.89-0.97), Mixed (aRR 0.85, CI 0.79-0.92) and Other ethnic groups (aRR 0.90, CI 0.85-0.96). Patients from minority ethnic backgrounds, particularly Black and South Asian, more often experienced ≥2 ED visits and ≥2 hospital admissions.

conclusionMinority ethnic patients with cancer receive fewer opioids and experience higher acute care use near the end of life. Tackling system-level inequities is critical to achieving pain management.

Indexed as

Analgesics, OpioidCancer PainEmergency Service, HospitalHealthcare DisparitiesHospitalizationNeoplasmsPractice Patterns, Physicians'AdultAgedAged, 80 and overDrug PrescriptionsEmergency Room VisitsEthnicityFemaleHumansMaleAnalgesics, Opioid

Identifiers

PMID40998950
PMCPMC12644774

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.