Evidence map›Paper›PMID 40998940›Full record

ArticleScientific reports2025

Neighborhood level socioeconomic disparities are associated with reduced colorectal cancer survival.

Holli A Loomans-Kropp, Mohamed I Elsaid, Yesung Kweon, Anne M Noonan, Peter P Stanich, Jesse Plascak, Matthew F Kalady, Chyke A Doubeni, Electra D Paskett

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Holli A Loomans-Kropp *Division of Cancer Prevention and Control, Department of Internal Medicine, College of Medicine, The Ohio State University, 3650 Olentangy River Road, Suite 224, Columbus, OH, 43214, USA. holli.loomans-kropp@osumc.edu.
Mohamed I Elsaid *The Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, USA.
Yesung KweonDepartment of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, OH, 43210, USA.
Anne M NoonanThe Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, USA.
Peter P StanichThe Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, USA.
Jesse PlascakDivision of Cancer Prevention and Control, Department of Internal Medicine, College of Medicine, The Ohio State University, 3650 Olentangy River Road, Suite 224, Columbus, OH, 43214, USA.
Matthew F KaladyThe Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, USA.
Chyke A Doubeni *The Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, USA.
Electra D Paskett *Division of Cancer Prevention and Control, Department of Internal Medicine, College of Medicine, The Ohio State University, 3650 Olentangy River Road, Suite 224, Columbus, OH, 43214, USA.

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Jennifer A. Woyach · 1985 to 2026
$132.3M
NCI NIH HHS P30 CA016058
6 · The paper itself

Abstract

We evaluated the relationship between residing in persistent poverty (PP) and low socioeconomic census tracts on all-cause and colorectal cancer (CRC)-specific mortality, providing a current assessment of economic disadvantage and health outcomes. Using Surveillance, Epidemiology, and End Results Program Data (2006-2020), CRC cases were identified using ICD-10 codes and stage I-III were included in the analysis. Overlap propensity score weighting with marginal structural models estimated the risk of all-cause and CRC-specific mortality. Individuals living in PP had higher risk of all-cause mortality at 15-year follow-up, with an adjusted risk difference (ARD) and adjusted risk ratio (aRR) of 7.2 (95% CI 5.9-8.7) and 1.1 (95% CI 1.1-1.1), respectively, with similar results for CRC-specific mortality. Individuals living in low socioeconomic census tracts had higher risk of all-cause (ARD: 5.3, 95% CI 4.0-6.6; aRR: 1.1, 95% CI 1.6-1.1) and CRC-specific mortality (ARD: 2.7, 95% CI 1.7-3.7; aRR: 1.1, 95% CI 1.1-1.1) at 15-year follow-up. Thus, residing in PP or low socioeconomic census tract may impact health outcomes.

Indexed as

Colorectal NeoplasmsHealth Status DisparitiesNeighborhood CharacteristicsAgedFemaleHumansMaleMiddle AgedPovertyResidence CharacteristicsSEER ProgramSocioeconomic Disparities in HealthSocioeconomic FactorsUnited StatesColorectal cancerHealth outcomesMortalityPersistent povertySocioeconomic status

Identifiers

PMID40998940
PMCPMC12464318

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.