Evidence map›Paper›PMID 40998832›Full record

ArticleNature communications2025

Facilitating analysis and dissemination of proteomics data through metadata integration in MaxQuant.

Walter Viegener, Shamil Urazbakhtin, Daniela Ferretti, Jürgen Cox, Jinqiu Xiao

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Walter Viegener *Computational Systems Biochemistry Research Group, Max Planck Institute of Biochemistry, Max Planck Institute of Biochemistry, Martinsried, Germany.ORCID http://orcid.org/0009-0008-6070-1868
Shamil Urazbakhtin *Computational Systems Biochemistry Research Group, Max Planck Institute of Biochemistry, Max Planck Institute of Biochemistry, Martinsried, Germany.ORCID http://orcid.org/0000-0002-1538-1745
Daniela FerrettiComputational Systems Biochemistry Research Group, Max Planck Institute of Biochemistry, Max Planck Institute of Biochemistry, Martinsried, Germany.
Jürgen CoxComputational Systems Biochemistry Research Group, Max Planck Institute of Biochemistry, Max Planck Institute of Biochemistry, Martinsried, Germany. cox@biochem.mpg.de.ORCID http://orcid.org/0000-0001-8597-205X
Jinqiu XiaoComputational Systems Biochemistry Research Group, Max Planck Institute of Biochemistry, Max Planck Institute of Biochemistry, Martinsried, Germany. jxiao@biochem.mpg.de.ORCID http://orcid.org/0000-0002-4279-9565

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metadata plays an essential role in the analysis and dissemination of proteomics data. It annotates sample information for output tables from library searches and displays sample information from data files in public repositories. However, integrating metadata into data analysis can be time-consuming and is not well standardized. Inconsistent metadata formats in public repositories hinder other researchers' ability to reproduce and reuse these public datasets. Here we present the metadata integration in MaxQuant, which provides a user-friendly way to export metadata as SDRF, the standard format that maps sample properties to proteomics data files. We also implemented the annotation of output tables with the SDRF file, enabling users to perform seamless downstream data analysis with annotated output tables. These features provide a simple and standardized approach to creating and leveraging standardized metadata, thereby facilitating data analysis and improving the reusability and reproducibility of public proteomics datasets.

Indexed as

Information DisseminationMetadataProteomicsSoftwareDatabases, ProteinHumansReproducibility of Results

Identifiers

PMID40998832
PMCPMC12462489

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.