Evidence map›Paper›PMID 40998584›Full record

ArticleRenal failure2025

Acute kidney injury among patients aged over 80 years after percutaneous coronary intervention: a multicenter, retrospective cohort study.

Xin Liu, Dingyi Wang, Yalin Cheng, Huimin Li, Yuzhu Lu, Haiyang Gao, Jing Ma, Chaozeng Si, Tingyu Yin, Guohui Fan and 1 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Xin LiuDepartment of Nephrology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
Dingyi WangNational Center for Respiratory Medicine, State Key Laboratory of Respiratory Health and Multimorbidity, National Clinical Research Center for Respiratory Diseases, Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Department of Clinical Research and Data Management, Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing, China.ORCID 0000-0002-5754-029X
Yalin ChengDepartment of Cardiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
Huimin LiDepartment of Cardiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yuzhu LuDepartment of Cardiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Haiyang GaoDepartment of Cardiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
Jing MaNational Center for Respiratory Medicine, State Key Laboratory of Respiratory Health and Multimorbidity, National Clinical Research Center for Respiratory Diseases, Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing, China.
Chaozeng SiInformation Center, China-Japan Friendship Hospital, Beijing, China.
Tingyu YinInformation Center, China-Japan Friendship Hospital, Beijing, China.
Guohui FanNational Center for Respiratory Medicine, State Key Laboratory of Respiratory Health and Multimorbidity, National Clinical Research Center for Respiratory Diseases, Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Department of Clinical Research and Data Management, Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing, China.ORCID 0000-0001-5187-1867
Wenduo ZhangDepartment of Cardiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to investigate the incidence and risk factors of acute kidney injury (AKI) after percutaneous coronary intervention (PCI) in the oldest-old patients (≥80 years), particularly among those with baseline renal insufficiency and peri-operative hydration.

methodsThis retrospective cohort study included patients ≥80 years undergoing PCI at two tertiary hospitals in China (hospitalized between January 2020 and December 2024). Baseline renal dysfunction was defined as eGFR < 60 mL/min/1.73 m

resultsAmong the 995 patients included in the final analysis, the incidence of baseline renal insufficiency was 35.9% and that of AKI was 13.8%. Logistic regression showed that STEMI, NSTEMI, acute heart failure, baseline renal insufficiency, a higher neutrophil-to-lymphocyte ratio (NLR), and anemia were independent risk factors for AKI. Among those with baseline renal insufficiency, AKI incidence was 29.7%, and lower baseline eGFR, elevated NLR, and preoperative diuretic use were independent risk factors for AKI. RCS analysis revealed that the AKI risk was significantly increased when eGFR < 67.4 mL/min/1.73 m

conclusionPatients ≥ 80 years old with baseline renal failure confronted higher AKI risk after PCI procedure. Comprehensive strategies beyond hydration may be needed for AKI prevention in this fragile population.

Indexed as

Acute Kidney InjuryPercutaneous Coronary InterventionPostoperative ComplicationsAged, 80 and overChinaFemaleGlomerular Filtration RateHospital MortalityHumansIncidenceLength of StayLogistic ModelsMaleRenal Replacement TherapyRetrospective StudiesRisk Factorsacute kidney injuryhydrationOldest-oldpercutaneous coronary interventionrenal dysfunction

Identifiers

PMID40998584
PMCPMC12466182

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.