ArticleThe Journal of international medical research2025
Risk analysis of cardiac disease mortality within 3 months in patients with lung cancer after surgery: A real-world cohort study.
Article in The Journal of international medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
ObjectiveTo determine the 3-month heart disease-related mortality rate among patients with lung cancer who have undergone lobectomy and identify the common risk factors for mortality to provide a basis for clinical risk assessment and intervention strategies.MethodsWe conducted a retrospective cohort study using the Surveillance, Epidemiology, and End Results Program database (2010-2015), including 35,094 patients with stage I-III lung cancer who underwent surgery. Logistic regression analyzed mortality at 3, 7, and 11 months, focusing on non-cancer causes, particularly heart diseases.ResultsAmong the 35,094 patients, 3.24% (1138) died within 3 months, with heart disease accounting for 8.96% (102) of the deaths, a significantly higher percentage than that at 4-7 months (p = 0.017). Logistic regression analysis showed that several factors, including sex, age, postoperative radiotherapy, and postoperative systematic treatment were independent factors contributing to mortality owing to heart diseases within 3 months of surgery.ConclusionsIn this study, we analyzed the causes of early death in patients who had undergone lung cancer surgery and determined the independent risk factors associated with 3-month mortality due to heart disease in these patients.
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