Evidence map›Paper›PMID 40997329›Full record

ArticleObstetrics and gynecology2026

Relationship Between Maternal Death and Infant Outcomes in a Longitudinal, Population-Based Dataset.

Eugene Declercq, Chia-Ling Liu, Howard J Cabral, Ndidiamaka Amutah-Onukagha, Sunah Hwang, Hafsatou Diop

Abstract read
In one paragraph

Article in Obstetrics and gynecology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eugene DeclercqEvalogic Services, Inc, Newton, and the Boston University School of Public Health, the Tufts University School of Medicine, and the Massachusetts Department of Public Health, Boston, Massachusetts; and the University of Colorado Anschutz Medical Campus, Aurora, Colorado.
Chia-Ling Liu
Howard J Cabral
Ndidiamaka Amutah-Onukagha
Sunah Hwang
Hafsatou Diop

Funding

Reducing Racial Disparities in SMM post COVID19: Assessing the integration of maternal safety bundles and community based doulas to improve outcomes for Black womenR01MD016026 · NIMHD · TUFTS UNIVERSITY BOSTON · PI AMUTAH-ONUKAGHA, NDIDIAMAKA, DECLERCQ, EUGENE R · 2020 to 2024
$3.1M
National Institute of Health NIH R01: MD016026NIMHD NIH HHS R01 MD016026
6 · The paper itself

Abstract

objectiveTo estimate the association between pregnancy-associated death or severe maternal morbidity and infant outcomes.

methodsWe conducted a retrospective cohort study using Massachusetts statewide data from 1999 to 2021. The dataset included hospital records longitudinally linked to births and maternal and infant death records. The primary exposures were pregnancy-associated death (deaths during pregnancy or in the year postpartum), severe maternal morbidity, and pregnancy-associated death after severe maternal morbidity. The main outcomes were infant death in the first year and, for those infants who survived, hospitalization in the first year of life. Bivariate and robust Poisson regression analyses through generalized estimating equations regression were used to estimate the association between the exposures and outcomes.

resultsOf 1,617,054 live births in Massachusetts between 1999 and 2020, there were 474 pregnancy-associated deaths. Pregnancy-associated death ratios were highest among individuals who were aged 40 years or older (49.3/100,000), who were non-Hispanic Black (43.0/100,000), who had public insurance (51.1/100,000), or who had a parity of four or more (80.6/100,000). Among individuals experiencing severe maternal morbidity (745.3/100,000), those who had a hospital encounter associated with opioid use (721.2/100,000) or a documented prepregnancy comorbidity (200.7/100,000) had the highest pregnancy-associated death ratios. In cases of pregnancy-associated death, the infant mortality rate per 1,000 live births was 55.0 (95% CI, 34.9-75.2) compared with 4.0 (95% CI, 3.9-4.1) when the mother survived. When the pregnancy-associated death followed severe maternal morbidity, the infant mortality rate was 87.9 per 1,000 live births (95% CI, 29.7-146.1). After a pregnancy-associated death, when a full-term infant survived to 1 year of age, there was a 35% greater likelihood of rehospitalization in the first year of life (adjusted risk ratio 1.35, 95% CI, 1.01-1.82) than when the mother did not die.

conclusionPregnancy-associated death was associated with infant death and worse health of surviving children in the first year of life, further demonstrating the far-reaching consequences of maternal deaths and the clear link between maternal and infant health.

Indexed as

Infant MortalityMaternal DeathMaternal MortalityPregnancy ComplicationsAdultFemaleHumansInfantInfant, NewbornLongitudinal StudiesMassachusettsPregnancyRetrospective StudiesYoung Adult

Identifiers

PMID40997329
PMCPMC12469818

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.