Evidence map›Paper›PMID 40997277›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Next-Generation Piezoelectric Materials in Wearable and Implantable Devices for Continuous Physiological Monitoring.

Bangul Khan, Umay Amara, Bilawal Khan, Wasim Ullah Khan, Rafi U Shan Ahmad, Muhammad Shehzad Khan, Mohamed Elhousseini Hilal, Bee Luan Khoo

Abstract readReview
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bangul KhanDepartment of Biomedical Engineering, College of Biomedicine, City University of Hong Kong, Tat Chee Ave, Kowloon, Hong Kong, China.ORCID https://orcid.org/0000-0001-5924-1667
Umay AmaraSchool of Materials Science and Engineering, Anhui University, Hefei, 230601, China.
Bilawal KhanDepartment of Materials Science and Engineering, City University of Hong Kong, Kowloon, Hong Kong, China.
Wasim Ullah KhanHong Kong Centre of Cerebro-Cardiovascular Health Engineering (COCHE), Shatin, Hong Kong, China.
Rafi U Shan AhmadDepartment of Biomedical Engineering, College of Biomedicine, City University of Hong Kong, Tat Chee Ave, Kowloon, Hong Kong, China.
Muhammad Shehzad KhanDepartment of Biomedical Engineering, College of Biomedicine, City University of Hong Kong, Tat Chee Ave, Kowloon, Hong Kong, China.
Mohamed Elhousseini HilalDepartment of Biomedical Engineering, College of Biomedicine, City University of Hong Kong, Tat Chee Ave, Kowloon, Hong Kong, China.
Bee Luan KhooDepartment of Biomedical Engineering, College of Biomedicine, City University of Hong Kong, Tat Chee Ave, Kowloon, Hong Kong, China.ORCID https://orcid.org/0000-0003-1100-9994

Funding

City University of Hong Kong 7006082City University of Hong Kong 7020002City University of Hong Kong 7020073City University of Hong Kong 7020110City University of Hong Kong 9609332City University of Hong Kong 9609333City University of Hong Kong 9678292Education Bureau Gifted Education Programme 3030780Hetao Shenzhen-Hong Kong Science and Technology Innovation Cooperation Zone Shenzhen Park Project HZQB-KCZYZ-2021017Hong Kong Center for Cerebro-Cardiovascular Health Engineering (COCHE), the Innovation and Technology Commission PRP/001/22FXInstitute of Digital Medicine, City University of Hong KongResearch Grants Council (RGC) 8799020Research Grants Council (RGC) 9043805Research Grants Council (RGC) 9048206
6 · The paper itself

Abstract

The rapid expansion of miniature biomedical devices has attracted considerable global attention, driven by the growing demand for advanced healthcare solutions. Despite significant progress in materials, fabrication techniques, and device architectures that have propelled the development of wearable and implantable technologies, a critical challenge remains: mimicking the structure and function of human skin. This challenge contrasts advancements in power efficiency, design miniaturization, precision, and device integration. Recent breakthroughs in manufacturing techniques and the development of high-performance organic and inorganic piezoelectric materials with tunable mechanical properties offer transformative potential to overcome these limitations. This review systematically examines the evolution of piezoelectric materials for health monitoring applications, focusing on their historical development, underlying mechanisms, fabrication strategies, and characterization techniques. We critically evaluate their integration into wearable and implantable systems, emphasizing their potential to address power autonomy, device adaptability, and sensing accuracy issues. Additionally, the article highlights emerging interdisciplinary research frontiers in bioengineering, highlighting pioneering contributions from global research teams. By synthesizing key advancements and identifying unresolved challenges, this review aims to provide a comprehensive guide for future innovations in smart biomedical devices, fostering collaborative efforts across the materials science, electronics, and healthcare fields.

Indexed as

Prostheses and ImplantsWearable Electronic DevicesEquipment DesignHumansMonitoring, PhysiologicHealth MonitoringImplantable DevicesPiezoelectric MaterialsWearable Devices

Identifiers

PMID40997277
PMCPMC12591194

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.