Evidence map›Paper›PMID 40997260›Full record

ArticleParasite (Paris, France)2025

Cryptosporidium spp. in wild rodents in the Poyang Lake region, China.

Qingqiu Zuo, Xiaodong Weng, Xu Wang, Hua Liu, Mingxiao Di, Xiaocheng Zhang, Bo Zhou, Chuizhao Xue, Ping Lu, Xiaoxue Peng and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Parasite (Paris, France), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Qingqiu Zuo *National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, WHO Collaborating Centre for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai 200025, PR China.ORCID 0009-0007-1344-6115
Xiaodong Weng *Institute of Biological Resources, Jiangxi Academy of Sciences, Nanchang 330096, PR China.
Xu WangNational Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, WHO Collaborating Centre for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai 200025, PR China.
Hua LiuNational Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, WHO Collaborating Centre for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai 200025, PR China.
Mingxiao DiInstitute of Biological Resources, Jiangxi Academy of Sciences, Nanchang 330096, PR China.
Xiaocheng ZhangNational Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, WHO Collaborating Centre for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai 200025, PR China.
Bo ZhouInstitute of Biological Resources, Jiangxi Academy of Sciences, Nanchang 330096, PR China.
Chuizhao XueNational Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, WHO Collaborating Centre for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai 200025, PR China.
Ping LuInstitute of Biological Resources, Jiangxi Academy of Sciences, Nanchang 330096, PR China.
Xiaoxue PengNational Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, WHO Collaborating Centre for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai 200025, PR China.
Yujuan ShenNational Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, WHO Collaborating Centre for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai 200025, PR China.
Jianping CaoNational Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, WHO Collaborating Centre for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai 200025, PR China - The School of Global Health, Chinese Center for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, PR China.

Funding

National Natural Science Foundation of China 32160264National Natural Science Foundation of China 82372283Natural Science Foundation of Jiangxi Province 20242BAB20266NHC Key Laboratory of Echinococcosis Prevention and Control 2024WZK1004
6 · The paper itself

Abstract

Cryptosporidium spp. are zoonotic protozoan parasites that cause diarrheal disease worldwide. Rodents can harbor diverse Cryptosporidium spp. and facilitate their transmission to the environment and other hosts, including humans. However, data on Cryptosporidium infection in wild rodents in the Poyang Lake region, China's largest freshwater lake, remain scarce. Here, we investigated Cryptosporidium spp. in 273 wild rodents collected from seven sites adjacent to villages around Poyang Lake between 2022 and 2024. The rodents were identified by cytochrome c oxidase subunit I (COI) gene sequencing as Apodemus agrarius (n = 148) and Rattus losea (n = 125). Nested PCR targeting the small subunit ribosomal RNA (SSU rRNA) gene revealed an overall Cryptosporidium spp. infection rate of 16.5% (45/273, 95% CI: 12.3-21.9%), with 20.3% (30/148, 95% CI: 14.2-27.8%) in A. agrarius and 12.0% (15/125, 95% CI: 6.9-19.0%) in R. losea. Sequence and phylogenetic analyses identified seven Cryptosporidium species/genotypes: C. apodemi, C. canis, C. muris, C. suis, C. ubiquitum, rat genotype II, and rat genotype III. Notably, the detection of four zoonotic species (C. canis, C. muris, C. suis, and C. ubiquitum) highlights the potential risk of zoonotic transmission of Cryptosporidium spp. from wild rodents to humans in this region. These findings underscore the need for systematic surveillance and control of Cryptosporidium spp. in wild rodent communities around Poyang Lake.

Indexed as

CryptosporidiosisCryptosporidiumMurinaeRodent DiseasesAnimalsAnimals, WildChinaDNA, ProtozoanFecesGenotypeHumansLakesPhylogenyPolymerase Chain ReactionRatsRodentiaDNA, ProtozoanApodemus agrariusCryptosporidiumPoyang Lake regionRattus loseaWild rodentsZoonotic

Identifiers

PMID40997260
PMCPMC12463348

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.