Evidence map›Paper›PMID 40997252›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2025

Middle meningeal artery embolization as a stand-alone treatment for primary and recurrent chronic subdural hematoma.

Bilandzic Josko, Bukna Marko, Gajski Domagoj, Francic Manuela, Martinis Frane, Culo Branimir, Kalousek Vladimir

Expression of concernAbstract read
In one paragraph

Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It carries an expression of concern. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Bilandzic JoskoDepartment of Neurosurgery, University Hospital Center Sestre Milosrdnice, Zagreb, Croatia.ORCID 0000-0002-2150-5433
Bukna MarkoDepartment of Radiology, University Hospital Center Sestre Milosrdnice, Zagreb, Croatia.
Gajski DomagojDepartment of Neurosurgery, University Hospital Center Sestre Milosrdnice, Zagreb, Croatia.ORCID 0000-0002-2517-5726
Francic ManuelaDepartment of Neurosurgery, University Hospital Center Sestre Milosrdnice, Zagreb, Croatia.
Martinis FraneDepartment of Neurosurgery, University Hospital Center Split, Split, Croatia.
Culo BranimirDepartment of Radiology, University Hospital Center Sestre Milosrdnice, Zagreb, Croatia.
Kalousek VladimirDepartment of Radiology, University Hospital Center Sestre Milosrdnice, Zagreb, Croatia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectiveChronic subdural hematoma (cSDH) is one of the most common neurosurgical emergencies. Due to high percentage of hematoma reaccumulation middle meningeal artery (MMA) embolization arose as an alternative treatment option. Aim of this retrospective study is to present single center results of 97 stand-alone embolization procedures done during 3-year period.MethodsProspectively maintained database of all patients who underwent MMA embolization from December 2021 to March 2025 was retrospectively analyzed. Seventy-five asymptomatic or mildly symptomatic patients with 97 hematomas were included; 72 MMA embolization procedures were done as primary treatment in 55 patients, whereas cSDH recurrency was main indication for 25 procedures in 20 patients. Primary and recurrent cSDH groups were compared using Chi-square test.ResultsMean follow-up period was 140 days. During the follow-up period 19/97 (19.6%) hematomas resorbed completely. Moreover, 21/97 (21.6%) of hematomas reduced in size more than 50%; 40 out of 97 embolized hematomas (41.2%) remained stable or were resorbed partially during follow up. Middle meningeal artery embolization failed in 14 cases (14.4%). We noted three cases of asymptomatic hematoma progression (3.1%). Three patients died during follow-up period. No statistically significant difference was shown between primary and recurrent cSDH cohort when compared based on percentage of complete hematoma resolution, treatment failure and rate of hematomas with >50% resorption.ConclusionsMiddle meningeal artery embolization is both safe and feasible stand-alone treatment option for cSDH, primarily for asymptomatic and minimally symptomatic patients with maximal hematoma tickness in the range between 10 and 20 mm.

Indexed as

liquid embolizationMMA embolizationprimary cSDHrecurrent cSDH

Identifiers

PMID40997252
PMCPMC12463866

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.