Evidence map›Paper›PMID 40997033›Full record

ArticlePloS one2025

Social determinants of self-medication with leftover antibiotics in Lebanese households: A cross-sectional study.

Reve Khaddaj, Pascale Salameh, Amal Al-Hajje, Julia Bou Dib, Joumana Yeretezian, Michele Cherfane, Reham Kotb, Diana Nakhoul, Reem Awad, Katia Iskandar

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Reve KhaddajFaculty of Pharmacy, Lebanese University, Beirut, Lebanon.ORCID https://orcid.org/0009-0000-9795-5767
Pascale SalamehFaculty of Pharmacy, Lebanese University, Beirut, Lebanon.
Amal Al-HajjeFaculty of Pharmacy, Lebanese University, Beirut, Lebanon.
Julia Bou DibHigher Institute of Public Health (ISSP), Saint Joseph University of Beirut, Lebanon.ORCID https://orcid.org/0009-0001-4343-287X
Joumana YeretezianHigher Institute of Public Health (ISSP), Saint Joseph University of Beirut, Lebanon.ORCID https://orcid.org/0000-0001-5805-4915
Michele CherfaneGilbert and Rose Marie Chagoury School of Medicine, Lebanese American University, Byblos, Lebanon.
Reham KotbEnvironmental and Public Health Department, College of Health Sciences, Abu Dhabi University, Abu Dhabi, UAE.
Diana NakhoulFaculty of Pharmacy, Lebanese University, Beirut, Lebanon.
Reem AwadFaculty of Pharmacy, Lebanese University, Beirut, Lebanon.
Katia IskandarINSPECT-LB (Institut National de Santé Publique, d'Épidémiologie Clinique et de Toxicologie-Liban), Beirut, Lebanon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSelf-medication with leftover antibiotics (LA) is a global health crisis, particularly in contexts of economic and political instability. This study examines the social determinants of health (SDOH) influencing LA use among Lebanese households, focusing on how individuals are born, grow, live, and work.

methodsA cross-sectional study was conducted among 368 Lebanese adults to collect data on socio-demographic characteristics, self-medication practices related to LA, and key SDOH such as socioeconomic status (SES), perceived discrimination in medical settings (DMS), political and economic instability, drug shortages, and trusted sources of health information. Data were analyzed using bivariate tests and multivariable logistic regression.

resultsBivariate analysis showed that LA use was significantly associated with male gender (45.0% vs. 33.3%, p = 0.024), lower educational levels (58.7% vs. 35.1%, p = 0.002), presence of chronic disease (54.7% vs. 32.2%, p < 0.001), older age (p = 0.028), and a higher household crowding index (p = 0.018). LA use was also more prevalent among participants impacted by political instability, economic crisis, and drug shortages (all p < 0.001). In multivariable logistic regression, chronic disease (OR = 2.711, p = 0.002), economic crisis (OR = 2.013, p < 0.001), and prior experience with the same illness (OR = 4.085, p < 0.001) were identified as significant predictors for LA use.

conclusionThese findings show the critical role of socio-economic instability, healthcare access challenges, and experiential factors as key SDOH driving LA practices. The study highlights the urgent need for multi-sectoral interventions addressing economic hardship, improving healthcare access, and enhancing public awareness to mitigate LA misuse and its contribution to antimicrobial resistance in Lebanon.

Indexed as

Anti-Bacterial AgentsSelf MedicationSocial Determinants of HealthAdolescentAdultAgedCross-Sectional StudiesFamily CharacteristicsFemaleHumansLebanonMaleMiddle AgedSocial ClassSocioeconomic FactorsYoung AdultAnti-Bacterial Agents

Identifiers

PMID40997033
PMCPMC12463266

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.