Evidence map›Paper›PMID 40996814›Full record

ArticleClinical journal of the American Society of Nephrology : CJASN2025

Associations of Plasma Trimethylamine N -Oxide-Related Metabolites with the Development and Progression of Albuminuria : The Multiethnic Study of Atherosclerosis.

Meng Wang, W H Wilson Tang, Xinmin S Li, Marcia C de Oliveira Otto, Rozenn N Lemaitre, Amanda Fretts, Ina Nemet, Nona Sotoodehnia, Colleen M Sitlani, Matthew Budoff and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical journal of the American Society of Nephrology : CJASN, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Gut Microbiota Metabolites and the Development of CKD.Clinical journal of the American Society of Nephrology : CJASN · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Meng WangFriedman School of Nutrition Science and Policy, Tufts University, Boston, Massachusetts.ORCID 0000-0001-8345-9180
W H Wilson TangDepartment of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland, Ohio.ORCID 0000-0002-8335-735
Xinmin S LiDepartment of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland, Ohio.ORCID 0000-0003-4946-4271
Marcia C de Oliveira OttoDivision of Epidemiology, Human Genetics and Environmental Sciences, The University of Texas Health Science Center at Houston (UTHealth) School of Public Health, Houston, Texas.ORCID 0000-0002-4585-0688
Rozenn N LemaitreCardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington.ORCID 0000-0002-7038-1844
Amanda FrettsCardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington.ORCID 0000-0002-5358-2345
Ina NemetDepartment of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland, Ohio.ORCID 0000-0002-0657-7121
Nona SotoodehniaCardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington.
Colleen M SitlaniCardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington.ORCID 0000-0001-7656-7482
Matthew BudoffLundquist Institute at Harbor-UCLA Medical Center, Torrance, California.ORCID 0000-0002-9616-1946
Joseph A DiDonatoDepartment of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland, Ohio.ORCID 0000-0002-1641-1758
Zeneng WangDepartment of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland, Ohio.ORCID 0000-0002-6455-8228
David S SiscovickThe New York Academy of Medicine, New York, New York.ORCID 0000-0003-0461-175
Mark J SarnakDepartment of Medicine (Nephrology), Tufts University School of Medicine, Boston, Massachusetts.ORCID 0000-0003-1860-6302
Dariush MozaffarianFriedman School of Nutrition Science and Policy, Tufts University, Boston, Massachusetts.
Stanley L HazenDepartment of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland, Ohio.ORCID 0000-0001-7124-6639

Funding

Project 3: Microbiota generated aryl sulfates and secondary bile acids in cardiometabolic diseaseP01HL147823 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI MICHAEL ANDREW FISCHBACH · 2019 to 2026
$17.0M
Gut Flora Metabolism of Dietary Phosphatidylcholine and CVDR01HL103866 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI HAZEN, STANLEY L · 2010 to 2023
$10.8M
TMAO and Initiation, Extent, and Clinical Onset of Atherosclerotic CVDR01HL135920 · NHLBI · TUFTS UNIVERSITY BOSTON · PI Stanley L Hazen, DARIUSH MOZAFFARIAN · 2017 to 2026
$8.7M
American Heart Association 906562NCATS NIH HHS UL1-TR-000040, UL1-TR-001079, and UL1-TR-001420NHLBI NIH HHS 75N92020D00001, HHSN268201500003I, N01-HC-95159, 75N92020D00005, N01-HC-95160, 75N92020D00002, N01-HC-95161, 75N92020D00003, N01-HC-95162, 75N92020D00006, N01-HC-95163, 75N92020D00004, N01-HC-95164, 75N92020D00007, N01-HC-95165, N01-HC-95166, N01-HC-95167, N01-HC-95168 and N01-HC-95169NHLBI NIH HHS P01 HL147823NHLBI NIH HHS R01 HL103866NHLBI NIH HHS R01 HL135920NHLBI NIH HHS R01HL135920NIH HHS R01 HL103866
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

albuminuriaCKDclinical epidemiologycohort studiesnutritionrisk factors

Identifiers

PMID40996814
PMCPMC12614857

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.