Evidence map›Paper›PMID 40996798›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Evolution under vancomycin selection drives divergent collateral sensitivity patterns in

Kyle J Card, Dena Crozier, Arda Durmaz, Jason Gray, Justin Creary, Amira Stocks, Jeff Maltas, Robert A Bonomo, Zachary D C Burke, Jacob G Scott

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Evolution under vancomycin selection drives divergent collateral sensitivity patterns inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Kyle J Card *Department of Genomic Medicine, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH 44106.ORCID 0000-0002-0462-2777
Dena Crozier *Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH 44106.
Arda DurmazDepartment of Genomic Medicine, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH 44106.
Jason GrayDepartment of Physics, Case Western Reserve University, Cleveland, OH 44106.
Justin CrearyDepartment of Genomic Medicine, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH 44106.ORCID 0009-0009-5426-4224
Amira StocksDepartment of Genomic Medicine, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH 44106.
Jeff MaltasDepartment of Physics, Case Western Reserve University, Cleveland, OH 44106.
Robert A BonomoMedical Service, Louis Stokes Cleveland Department of Veteran Affairs Medical Center, Cleveland, OH 44106.ORCID 0000-0002-3299-894X
Zachary D C BurkeDepartment of Genomic Medicine, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH 44106.ORCID 0000-0001-9601-0956
Jacob G ScottDepartment of Genomic Medicine, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH 44106.ORCID 0000-0003-2971-7673

Funding

Exploiting Ecology and Evolution to Prevent Therapy Resistance in EGFR-Driven Lung CancerR37CA244613 · NCI · CLEVELAND CLINIC LERNER COM-CWRU · PI Jacob Gardinier Scott · 2020 to 2026
$4.0M
HHS | NIH (NIH) 5R37CA244613-02NCI NIH HHS R37 CA244613
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anti-Bacterial AgentsStaphylococcus aureusVancomycinBacterial ProteinsDrug Resistance, BacterialEvolution, MolecularHumansMicrobial Sensitivity TestsMutationSelection, GeneticStaphylococcal InfectionsAnti-Bacterial AgentsBacterial ProteinsVancomycinantibiotic resistancecollateral sensitivityexperimental evolutionparallel evolutionStaphylococcus aureus

Identifiers

PMID40996798
PMCPMC12501141

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.