Evidence map›Paper›PMID 40996714›Full record

ArticleDatabase : the journal of biological databases and curation2025

GExplore 1.5: a comprehensive Caenorhabditis elegans database for the analysis of gene function with a new user-friendly web interface.

Harald Hutter, Mehrdad Moosavi, Nelly Mafi

Abstract read
In one paragraph

Article in Database : the journal of biological databases and curation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Harald HutterDepartment of Biological Sciences, Simon Fraser University, 8888 University Drive Burnaby, BC V5A 1S6, Canada.ORCID 0000-0002-1162-4199
Mehrdad MoosaviDepartment of Biological Sciences, Simon Fraser University, 8888 University Drive Burnaby, BC V5A 1S6, Canada.
Nelly MafiEmily Carr University of Art and Design, 520 1st Ave E. Vancouver, BC V5T 0H2, Canada.

Funding

National Sciences and Engineering Research Council RGPIN-2023-05210
6 · The paper itself

Abstract

GExplore is an online tool to assist with large-scale data mining of selected datasets related to gene and protein function in Caenorhabditis elegans. Here, we describe the current version GExplore 1.5, which contains new datasets and display options as well as a completely redesigned web interface. GExplore now consists of six databases. The gene database contains protein domain information, general expression, and phenotype data as well as interacting genes, gene ontology annotations, and disease associations. The mutation database contains a curated list of more than 200 000 mutations affecting the protein sequences of all protein-coding genes. The protein database contains proteome data from 19 different nematode species, four genetic model organisms and the human proteome for comparison. Three genome-scale RNAseq expression databases contain expression profiles of different developmental stages from embryo to adult, tissues-specific expression profiles at the L2 stage, and expression profiles of the major tissues in the developing embryo at five different time points from gastrulation to the beginning of terminal differentiation. The web-based user interface has been completely redeveloped for the current version. The search interfaces allow users to explore content of the individual databases in detail. The interactive display pages enable the user to fine-tune the results, display additional data, and download the results. GExplore is a tool to quickly obtain an overview of biological and biochemical functions of large groups of genes or identify genes with a certain combination of features for further experimental analysis. Database URL: https://genome.science.sfu.ca/gexplore.

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsDatabases, GeneticInternetUser-Computer InterfaceAnimalsHumansSoftwareCaenorhabditis elegans Proteins

Identifiers

PMID40996714
PMCPMC12462625

What OpenQuestion holds

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.