Evidence map›Paper›PMID 40996701›Full record

ReviewDatabase : the journal of biological databases and curation2025

Integrated data-driven biotechnology research environments.

Rosalia Moreddu

Abstract readReview
In one paragraph

Review in Database : the journal of biological databases and curation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Rosalia MoredduSchool of Electronics and Computer Science, University of Southampton, University Road, SO17 1BJ, Southampton, United Kingdom.ORCID 0000-0002-0332-1606

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the past few decades, the life sciences have experienced an unprecedented accumulation of data, ranging from genomic sequences and proteomic profiles to heavy-content imaging, clinical assays, and commercial biological products for research. Traditional static databases have been invaluable in providing standardized and structured information. However, they fall short when it comes to facilitating exploratory data interrogation, real-time query, multidimensional comparison, and dynamic visualization. Integrated data-driven research environments aiming at supporting user-driven data queries and visualization offer promising new avenues for making the best use of the vast and heterogeneous data streams collected in biological research. This article discusses the potential of interactive and integrated frameworks, highlighting the importance of implementing this model in biotechnology research, while going through the state-of-the-art in database design, technical choices behind modern data management systems, and emerging needs in multidisciplinary research. Special attention is given to data interrogation strategies, user interface design, and comparative analysis capabilities, along with challenges such as data standardization and scalability in data-heavy applications. Conceptual features for developing interactive data environments along diverse life science domains are then presented in the user case of cell line selection for in vitro research to bridge the gap between research data generation, actionable biological insight, experimental design, and clinical relevance.

Indexed as

BiotechnologyDatabases, FactualHumansUser-Computer Interface

Identifiers

PMID40996701
PMCPMC12462373

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.