ArticleJournal of racial and ethnic health disparities2025
Racial and Ethnic Disparities in Cancer Mortality and Mediating Effects of Sociodemographic, Clinicopathologic, and Treatment Factors.
Article in Journal of racial and ethnic health disparities, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Mapping Ethnic Enclaves for Health Disparities Research: A Hybrid Clustering Approach.Journal of racial and ethnic health disparities · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo evaluate the associations between race/ethnicity and cancer-specific and all-cause mortality and to explore potential mediating factors.
methodsWe identified patients diagnosed with lung (22,866), colorectal (13,382), melanoma (6894), prostate (22,922), and breast (133,366) cancers between 2010 and 2019 from the Texas Cancer Registry. Differences in mortality risk among non-Hispanic Blacks, Asian American/Native Hawaiian/Pacific Islanders (AANHPI), and Hispanics compared to non-Hispanic Whites were estimated using Cox proportional hazard and restricted mean survival time analyses. Mediation analysis was conducted to quantify the contributions of socioeconomic, clinicopathologic, and treatment-related factors to observed mortality differences.
resultsRacial/ethnic disparities in survival were observed across all cancers, with the smallest disparity for lung cancer and the largest for melanoma and breast cancer. In age-and-sex-adjusted models, Blacks had higher mortality risks for all cancers observed. Hispanics showed higher mortality risks for non-small cell lung cancer, melanoma, and breast cancer, while AANHPIs had lower mortality risks for lung and breast cancer. After adjusting for demographic, clinical, and treatment factors, Blacks still had significantly higher mortality risks for melanoma (HR = 1.63, 95% CI = 1.49-1.70) and breast cancer (HR = 1.19, 95% CI = 1.09-1.30). Socioeconomic and clinicopathologic factors were major mediators of racial/ethnic disparities, accounting for 56.71% of the difference in melanoma mortality and 54.10% in breast cancer mortality between Blacks and Whites.
conclusionsRacial/ethnic disparities in cancer outcomes persist, particularly for melanoma and breast cancer among Black patients. Interventions promoting equity in cancer outcomes should be tailored by cancer type and take a multidisciplinary approach, integrating both social and biological factors to address disparities effectively.
Indexed as
Identifiers
40996688What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.