Evidence map›Paper›PMID 40996604›Full record

ArticleInsights into imaging2025

Segmentation-model-based framework to detect aortic dissection on non-contrast CT images: a retrospective study.

Qidong Wang, Shan Huang, Weifeng Pan, Zhan Feng, Lei Lv, Dongwei Guan, Zhiwen Yang, Yimin Huang, Wei Liu, Weiwei Shui and 2 more

Abstract read
In one paragraph

Article in Insights into imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Qidong Wang *Department of Radiology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Shan Huang *Department of Radiology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Weifeng PanDepartment of Radiology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Zhan FengDepartment of Radiology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Lei LvShuKun Technology Co., Ltd., Jinhui Bd, Beijing, China.
Dongwei GuanShuKun Technology Co., Ltd., Jinhui Bd, Beijing, China.
Zhiwen YangShuKun Technology Co., Ltd., Jinhui Bd, Beijing, China.
Yimin HuangShuKun Technology Co., Ltd., Jinhui Bd, Beijing, China.
Wei LiuDepartment of Radiology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Weiwei ShuiDepartment of Radiology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Mingliang YingDepartment of Radiology, Jinhua Municipal Central Hospital, Jinhua, China.
Wenbo XiaoDepartment of Radiology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China. xiaowenbo@zju.edu.cn.ORCID http://orcid.org/0000-0001-7124-1096

Funding

National Natural Science Foundation of China 82330060National Natural Science Foundation of China 82370738
6 · The paper itself

Abstract

objectivesTo develop an automated deep learning framework for detecting aortic dissection (AD) and visualizing its morphology and extent on non-contrast CT (NCCT) images. MATERIALS AND

methodsThis retrospective study included patients who underwent aortic CTA from January 2021 to January 2023 at two tertiary hospitals. Demographic data, medical history, and CT scans were collected. A segmentation-based deep learning model was trained to identify true and false lumens on NCCT images, with performance evaluated on internal and external test sets. Segmentation accuracy was measured using the Dice coefficient, while the intraclass correlation coefficient (ICC) assessed consistency between predicted and ground-truth false lumen volumes. Receiver operating characteristic (ROC) analysis evaluated the model's predictive performance.

resultsAmong 701 patients (median age, 53 years, IQR: 41-64, 486 males), data from Center 1 were split into training (439 cases: 318 non-AD, 121 AD) and internal test sets (106 cases: 77 non-AD, 29 AD) (8:2 ratio), while Center 2 served as the external test set (156 cases: 80 non-AD, 76 AD). The ICC for false lumen volume was 0.823 (95% CI: 0.750-0.880) internally and 0.823 (95% CI: 0.760-0.870) externally. The model achieved an AUC of 0.935 (95% CI: 0.894-0.968) in the external test set, with an optimal cutoff of 7649 mm

conclusionsThe proposed deep learning framework accurately detects AD on NCCT and effectively visualizes its morphological features, demonstrating strong clinical potential. CRITICAL RELEVANCE STATEMENT: This deep learning framework helps reduce the misdiagnosis of AD in emergencies with limited time. The satisfactory results of presenting true/false lumen on NCCT images benefit patients with contrast media contraindications and promote treatment decisions. KEY POINTS: False lumen volume was used as an indicator for AD. NCCT detects AD via this segmentation model. This framework enhances AD diagnosis in emergencies, reducing unnecessary contrast use.

Indexed as

Aortic dissectionDeep learning.Non-contrast computed tomography

Identifiers

PMID40996604
PMCPMC12463791

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.