Evidence map›Paper›PMID 40996328›Full record

ArticleAnnals of the American Thoracic Society2026

Xenon-129 magnetic resonance imaging detects ongoing ventilation improvements in people with cystic fibrosis receiving highly effective modulator therapy.

Riaz Hussain, Bilal I Masokano, Joseph W Plummer, Abdullah S Bdaiwi, Matthew M Willmering, Elizabeth L Kramer, Laura L Walkup, Zackary I Cleveland

Abstract read
In one paragraph

Article in Annals of the American Thoracic Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Riaz HussainDivision of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.ORCID 0000-0003-4406-2345
Bilal I MasokanoDivision of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.ORCID 0000-0001-7777-9428
Joseph W PlummerDivision of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.ORCID 0000-0002-0200-7869
Abdullah S BdaiwiDivision of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.ORCID 0000-0001-7835-7032
Matthew M WillmeringDivision of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.ORCID 0000-0002-4356-9622
Elizabeth L KramerDivision of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.ORCID 0000-0002-3278-2161
Laura L WalkupDivision of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.ORCID 0000-0002-5060-6401
Zackary I ClevelandDivision of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.ORCID 0000-0001-6195-9061

Funding

Using MRI To Visualize Regional Therapy Response In Idiopathic Pulmonary FibrosisR01HL126771 · NHLBI · DUKE UNIVERSITY · PI Bastiaan Driehuys · 2015 to 2026
$6.6M
Imaging and Molecular Phenotyping of Cystic Fibrosis Lung DiseaseR01HL151588 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI CLEVELAND, ZACKARY I, ZIADY, ASSEM G · 2021 to 2025
$3.9M
Validating Quantitative Magnetic Resonance Imaging Biomarkers of Idiopathic Pulmonary FibrosisR01HL143011 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI CLEVELAND, ZACKARY I · 2019 to 2023
$3.7M
Early detection of pulmonary complications of hematopoietic stem-cell transplantation in children using hyperpolarized xenon MRIR01HL166335 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI Laura Lee Walkup · 2023 to 2026
$2.7M
NHLBI NIH HHS R01 HL126771NHLBI NIH HHS R01 HL143011NHLBI NIH HHS R01 HL151588NHLBI NIH HHS R01 HL166335NIH HHS 2R01HL126771NIH HHS R01HL143011NIH HHS R01HL151588NIH HHS R01HL166335
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40996328
PMCPMC12469796

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.