Evidence map›Paper›PMID 40996317›Full record

ReviewThe British journal of radiology2026

How can children benefit from total-body PET?

Johannes H van Snick, Oleksandra V Ivashchenko, Joyce van Sluis, Limme B de Langen, Georgiana C van den Oever, Mostafa Roya, Andor W J M Glaudemans, Riemer H J A Slart

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The British journal of radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Cardiovascular imaging with total-body PET.The British journal of radiology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Johannes H van SnickDepartment of Nuclear Medicine and Molecular Imaging, Medical Imaging Center, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.ORCID 0009-0008-0417-1823
Oleksandra V IvashchenkoDepartment of Nuclear Medicine and Molecular Imaging, Medical Imaging Center, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
Joyce van SluisDepartment of Nuclear Medicine and Molecular Imaging, Medical Imaging Center, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
Limme B de LangenDepartment of Paediatrics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
Georgiana C van den OeverDepartment of Nuclear Medicine and Molecular Imaging, Medical Imaging Center, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
Mostafa RoyaDepartment of Nuclear Medicine and Molecular Imaging, Medical Imaging Center, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
Andor W J M GlaudemansDepartment of Nuclear Medicine and Molecular Imaging, Medical Imaging Center, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
Riemer H J A SlartDepartment of Nuclear Medicine and Molecular Imaging, Medical Imaging Center, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.ORCID 0000-0002-5565-1164

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The introduction of long axial field-of-view (LAFOV) PET/CT scanners marks a major advancement in paediatric nuclear medicine. These systems provide greatly enhanced sensitivity, enabling superior image quality with reduced radiopharmaceutical doses and substantially shorter scan times. This is particularly advantageous in children, who are more radiosensitive and often struggle with prolonged procedures that may require sedation. LAFOV PET/CT allows whole-body imaging in a single bed position, reducing motion artefacts, improving patient comfort, and lessening procedural anxiety. Such benefits align with the ALARA (As Low As Reasonably Achievable) principle, critical for minimising radiation exposure in children given their increased sensitivity and longer life expectancy. Although associated with higher initial costs and increased data demands, LAFOV technology offers significant clinical advantages, including the potential for personalised imaging protocols tailored to each child's needs. This review discusses the technical attributes of LAFOV PET/CT and its expanding role in paediatric imaging, addressing both opportunities and challenges. By overcoming previous limitations related to scan duration and radiation dose, LAFOV PET/CT is poised to transform paediatric diagnostics, enabling safer, faster and more comprehensive assessments.

Indexed as

Positron Emission Tomography Computed TomographyWhole Body ImagingChildHumansRadiation DosageRadiopharmaceuticalsRadiopharmaceuticalsclinical applicationsimagingLAFOV PET/CTpaediatricsprocedures

Identifiers

PMID40996317
PMCPMC13489392

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.