Evidence map›Paper›PMID 40996227›Full record

ArticleMicrobiology spectrum2025

Earlier and prolonged respiratory syncytial virus (RSV) seasons in young children compared to adults: implications for prevention in infants.

Yuan Chao Xue, Natalie Williams-Bouyer, Ping Ren, Janak A Patel

Abstract read
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yuan Chao XueDepartment of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.ORCID 0000-0003-3306-3596
Natalie Williams-BouyerDepartment of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.
Ping RenDepartment of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.ORCID 0000-0002-4022-6667
Janak A PatelDepartment of Infection Control & Healthcare Epidemiology, University of Texas Medical Branch, Galveston, Texas, USA.ORCID 0009-0006-5467-5195

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Respiratory syncytial virus (RSV) poses a major health concern, particularly for young children and older adults. In this 10-year, single-center retrospective study (15 May 2015 to 14 May 2025), we analyzed RSV positivity rates to characterize local epidemiologic trends. When stratified by age, children ≤2 years consistently exhibited the highest positivity rates. Using the Centers for Disease Control and Prevention's 3% positivity threshold, we found that the RSV season in the general population in our region began in early July and ended in late December, approximately 3 months earlier than the national average. Among infants ≤2 years, the season lasted 5 weeks longer on average than in the general population. These findings highlight regional variability in RSV seasonality and the earlier onset and extended duration of RSV activity in young children. This age group appeared particularly susceptible and likely played a key role in initiating and sustaining community transmission. Monitoring RSV positivity specifically in children ≤2 years, separate from the general population, may enhance local surveillance accuracy and support more timely decisions regarding RSV immunoprophylaxis and vaccination strategies. IMPORTANCE: Respiratory syncytial virus (RSV) is a major health concern, especially for young children and older adults. In this study, we explored whether different age groups changed the timing of RSV season. This is important because public health guidelines, hospital preparedness, and preventive strategies like antibody prophylaxis and vaccination rely on accurate RSV season timing. By showing how RSV trends differ by age, our findings can help improve seasonality responses and ensure that preventive measures reach high-risk groups, especially infants, at the right time.

Indexed as

Respiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsSeasonsAdolescentAdultChildChild, PreschoolFemaleHumansInfantInfant, NewbornMaleRetrospective StudiesYoung AdultepidemiologypediatricsRSV seasonality

Identifiers

PMID40996227
PMCPMC12584610

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.