Evidence map›Paper›PMID 40996081›Full record

ArticleJournal of the American Heart Association2025

Interventional Partial Cavopulmonary Connection: Initial Clinical Experience With Acute Procedural up to Midterm Results.

Katarzyna Gendera, Peter Ewert, Stanimir Georgiev, Andreas Eicken, Daniel Tanase, Kristina Borgmann, Paul Philipp Heinisch, Nicole Nagdyman, Julie Cleuziou, Dunja Renner and 1 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Katarzyna GenderaDepartment of Pediatric Cardiology and Congenital Heart Defects TUM University Hospital, German Heart Center, Technical University of Munich Munich Germany.ORCID 0000-0001-6228-3550
Peter EwertDepartment of Pediatric Cardiology and Congenital Heart Defects TUM University Hospital, German Heart Center, Technical University of Munich Munich Germany.ORCID 0000-0003-0253-1190
Stanimir GeorgievDepartment of Pediatric Cardiology and Congenital Heart Defects TUM University Hospital, German Heart Center, Technical University of Munich Munich Germany.ORCID 0000-0002-6239-8160
Andreas EickenDepartment of Pediatric Cardiology and Congenital Heart Defects TUM University Hospital, German Heart Center, Technical University of Munich Munich Germany.
Daniel TanaseDepartment of Pediatric Cardiology and Congenital Heart Defects TUM University Hospital, German Heart Center, Technical University of Munich Munich Germany.ORCID 0000-0003-1723-1254
Kristina BorgmannDepartment of Pediatric Cardiology and Congenital Heart Defects TUM University Hospital, German Heart Center, Technical University of Munich Munich Germany.
Paul Philipp HeinischDepartment of Congenital and Paediatric Heart Surgery TUM University Hospital, German Heart Center, Technical University of Munich Munich Germany.
Nicole NagdymanDepartment of Pediatric Cardiology and Congenital Heart Defects TUM University Hospital, German Heart Center, Technical University of Munich Munich Germany.ORCID 0000-0002-4388-2678
Julie CleuziouDepartment of Congenital and Paediatric Heart Surgery TUM University Hospital, German Heart Center, Technical University of Munich Munich Germany.ORCID 0000-0002-1971-4375
Dunja RennerDepartment of Pediatric Cardiology and Congenital Heart Defects TUM University Hospital, German Heart Center, Technical University of Munich Munich Germany.ORCID 0009-0003-2144-3775
Pinar Bambul HeckDepartment of Pediatric Cardiology and Congenital Heart Defects TUM University Hospital, German Heart Center, Technical University of Munich Munich Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCreation of a partial cavopulmonary anasthomosis in patients with isolated right-sided heart failure or patients with cyanosis and intracardial right-to-left shunt and reduced blood flow in the pulmonary circulation may provide a significant improvement in exercise capacity and also facilitate the performance of activities of daily living in patients with a deteriorated clinical condition. However, surgical partial cavopulmonary connection creation may be a high-risk procedure in this patient group. An interventional partial cavopulmonary connection may provide a less invasive treatment modality for these patients. The aim of the study was a retrospective evaluation of patients who underwent the creation of an interventional partial cavopulmonary connection.

methodsEach patient who was qualified for treatment underwent a preinterventional computed tomography scan with 3-dimensional reconstruction for improved procedure planning. As a preparation preceding the interventional partial cavopulmonary connection, a prestent (bare metal stent) was implanted into the superior vena cava during cardiac catheterization in most cases. The perforation was performed with the use of needle punctures as a straightforward method in all cases. Thereafter, a covered stent was implanted, connecting the superior vena cava and the right pulmonary artery.

resultsBetween July 2019 and July 2024, 14 patients (male n=6, 43%) underwent an interventional partial cavopulmonary connection. The indication for treatment was deteriorated clinical condition (n=12, 86%) or significant cyanosis (n=2, 14%). The procedure was performed successfully in all cases. The median follow-up time was 19.8 months (minimum 2.7; maximum 65.6).

conclusionsOur study shows that transcatheter creation of partial cavopulmonary connection provides a promising treatment modality for selected adult patients with right-sided heart failure and may lead to clinical improvement in this patient group.

Indexed as

Cardiac CatheterizationFontan ProcedureHeart Bypass, RightHeart Defects, CongenitalPulmonary ArteryVena Cava, SuperiorAdolescentAdultChildFemaleHumansMaleRetrospective StudiesStentsTime FactorsTomography, X-Ray Computedadult congenital heart diseaseEbstein anomalypartial cavopulmonary connection (PCPC)right heart failuretranscatheter intervention

Identifiers

PMID40996081
PMCPMC12684551

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.