Evidence map›Paper›PMID 40996058›Full record

ArticleJournal of the American Heart Association2025

Racial Disparities in Heart Transplantation: Long-Term Graft Survival and Nonmortality Outcomes.

Steven Anthony Hamilton, Brian Wayda, Yingjie Weng, Shiqi Zhang, Kiran K Khush

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Unequal Hearts: Racial Disparities Persist in Heart Transplant Outcomes.Journal of the American Heart Association · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Steven Anthony HamiltonDepartment of Cardiology Kaiser Permanente San Francisco Medical Center San Francisco CA USA.ORCID 0000-0002-8539-4322
Brian WaydaDivision of Cardiovascular Medicine, Department of Medicine NYU Grossman School of Medicine New York NY USA.
Yingjie WengQuantitative Sciences Unit, Department of Medicine Stanford University Stanford CA USA.
Shiqi ZhangQuantitative Sciences Unit, Department of Medicine Stanford University Stanford CA USA.ORCID 0000-0001-8746-1931
Kiran K KhushDivision of Cardiovascular Medicine, Department of Medicine Stanford University Stanford CA USA.ORCID 0000-0001-9697-5926

Funding

More heart transplants through informed donor selectionK08HL177427 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Brian Wayda · 2025 to 2026
$331k
NHLBI NIH HHS K08 HL177427
6 · The paper itself

Abstract

backgroundPrior studies have reported conflicting evidence on racial disparities in heart transplant outcomes, often focusing only on short-term mortality rates. We assessed longer-term survival and a broader range of post-heart transplant outcomes by race.

methodsWe analyzed adult heart transplant recipients from 2017 to 2022 in the SRTR (Scientific Registry for Transplant Recipients), categorizing race as Black, non-Hispanic White, or Other. The primary outcome was graft failure at 1 and 3 years. Secondary outcomes included acute rejection, renal dysfunction, and posttransplant diabetes. χ

resultsAmong 15 873 recipients (63% White, 23% Black, 14% Other), Black recipients were more likely female, publicly insured, and less likely to be college educated. They also had higher use of durable ventricular assist devices and intra-aortic balloon pump at transplant. One-year graft survival was similar across groups (91.8% Black versus 91.1% non-Black), but 3-year survival was lower among Black individuals (83.4% versus 85.7%,

conclusionsRacial disparities in heart transplant outcomes persist, particularly in longer-term survival. These disparities may be partially mediated by differences in posttransplant complications such as rejection, renal dysfunction, and diabetes.

Indexed as

Black or African AmericanGraft RejectionGraft SurvivalHealthcare DisparitiesHeart TransplantationAdultFemaleHealth Status DisparitiesHumansMaleMiddle AgedRegistriesRetrospective StudiesRisk AssessmentRisk FactorsTime Factorsgraft survivalheart transplantationracial disparitiesrejectionrenal dysfunction

Identifiers

PMID40996058
PMCPMC12684610

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.