Evidence map›Paper›PMID 40996037›Full record

ArticlemSystems2025

Global proteomic analysis of

Jovany J Betancourt, Jason A McAlister, Jesenia M Perez, David B Meya, Stefani N Thomas, Jennifer Geddes-McAlister, Kirsten Nielsen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSystems, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Jovany J BetancourtDepartment of Microbiology and Immunology, University of Minnesota, Minneapolis, Minnesota, USA.ORCID 0000-0003-0364-4816
Jason A McAlisterDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada.
Jesenia M PerezMicrobiology, Immunology, and Cancer Biology Graduate Program, University of Minnesota, Minneapolis, Minnesota, USA.
David B MeyaInfectious Diseases Institute, Makerere University, Kampala, Uganda.
Stefani N ThomasDepartment of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA.
Jennifer Geddes-McAlisterDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada.ORCID 0000-0002-4257-2096
Kirsten NielsenDepartment of Microbiology and Immunology, University of Minnesota, Minneapolis, Minnesota, USA.ORCID 0000-0002-2318-168X

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM008244 · NIGMS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI SHIMIZU, YOJI · 1988 to 2024
$13.6M
TRAINING GRANT IN MICROBIOLOGY/CANCER RESEARCHT32CA009138 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Scott M. Dehm · 1985 to 2026
$11.3M
Genomic Research Capacity Building for Cryptococcosis Translational StudiesR01NS118538 · NINDS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI Joel Bazira, David Bisagaya Meya · 2020 to 2026
$3.4M
Continuum of Immune Responses to Cryptococcus neoformansR01AI176922 · NIAID · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI Kirsten Nielsen · 2023 to 2026
$3.0M
Assessing the role of SP140 in enhanced resistance to Cryptococcus neoformansF31AI181528 · NIAID · UNIVERSITY OF MINNESOTA · PI Jovany Jordan Betancourt · 2024 to 2026
$145k
NCI NIH HHS T32 CA009138NIAID NIH HHS F31 AI181528NIAID NIH HHS R01 AI176922NIGMS NIH HHS T32 GM008244NINDS NIH HHS R01 NS118538
6 · The paper itself

Abstract

To predict the outcomes of disseminated fungal disease, a deeper understanding of host-pathogen interactions at the site of infection is needed to identify targets for clinical intervention and diagnostic development.

Indexed as

CryptococcosisCryptococcus neoformansFungal ProteinsProteomeProteomicsAnimalsDisease Models, AnimalFemaleHost-Pathogen InteractionsHumansLungMiceVirulenceFungal ProteinsProteomeclinical isolatesCryptococcus neoformansimmune mechanismslung defenselung infectionproteomics

Identifiers

PMID40996037
PMCPMC12542649

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.