Evidence map›Paper›PMID 40996031›Full record

ArticlemBio2025

The

Sam F Feldstein, Kate M Rahbari, Trevor R Leonardo, Suzanne A Alvernaz, Ian McIntire, Richard Foster, Michael J Federle

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sam F FeldsteinDepartment of Microbiology and Immunology, University of Illinois - Chicago, Chicago, Illinois, USA.ORCID 0000-0002-5367-1313
Kate M RahbariDepartment of Microbiology and Immunology, University of Illinois - Chicago, Chicago, Illinois, USA.
Trevor R LeonardoDepartment of Microbiology and Immunology, University of Illinois - Chicago, Chicago, Illinois, USA.
Suzanne A AlvernazDepartment of Biomedical Engineering, University of Illinois - Chicago, Chicago, Illinois, USA.
Ian McIntireDepartment of Pharmaceutical Sciences, University of Illinois - Chicago, Chicago, Illinois, USA.
Richard FosterDepartment of Pharmaceutical Sciences, University of Illinois - Chicago, Chicago, Illinois, USA.
Michael J FederleDepartment of Pharmaceutical Sciences, University of Illinois - Chicago, Chicago, Illinois, USA.ORCID 0000-0002-4554-543X

Funding

Macrophage Immunosuppression by Quorum-Induced Streptococcus pyogenesR01AI162679 · NIAID · UNIVERSITY OF ILLINOIS AT CHICAGO · PI FEDERLE, MICHAEL J · 2022 to 2025
$2.4M
Streptococcus pyogenes manipulates host immunity via the Rgg2/3 quorum sensing systemF31AI147429 · NIAID · UNIVERSITY OF ILLINOIS AT CHICAGO · PI RAHBARI, KATE M · 2019 to 2021
$152k
National Institute of Allergy and Infectious Diseases AI162679National Institute of Allergy and Infectious Diseases F31AI147429NIAID NIH HHS F31 AI147429NIAID NIH HHS R01 AI162679
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bacterial ProteinsMacrophagesQuorum SensingStreptococcus pyogenesTrans-ActivatorsAnimalsEpigenesis, GeneticHumansInflammationMiceNF-kappa BProteomicsStreptococcal InfectionsBacterial ProteinsNF-kappa Brgg protein, StreptococcusTrans-Activatorsepigeneticsgroup A Streptococcusimmune evasioninnate immunitymacrophagesquorum sensing

Identifiers

PMID40996031
PMCPMC12607563

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.