Evidence map›Paper›PMID 40995533›Full record

ArticleJournal of biomedical optics2025

Improving vascular retention of indocyanine green for

Alankrit Tomar, Noah Stern, Tyrone Porter, Andrew K Dunn

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alankrit TomarThe University of Texas at Austin, Department of Electrical and Computer Engineering, Austin, Texas, United States.
Noah SternThe University of Texas at Austin, Department of Biomedical Engineering, Austin, Texas, United States.ORCID https://orcid.org/0000-0002-6390-8476
Tyrone PorterThe University of Texas at Austin, Department of Biomedical Engineering, Austin, Texas, United States.
Andrew K DunnThe University of Texas at Austin, Department of Electrical and Computer Engineering, Austin, Texas, United States.ORCID https://orcid.org/0000-0001-6500-5783

Funding

Comprehensive Training Program in Imaging Science and InformaticsT32EB007507 · NIBIB · UNIVERSITY OF TEXAS AT AUSTIN · PI MARKEY, MIA K, RYLANDER, HENRY GRADY · 2009 to 2024
$2.7M
NIBIB NIH HHS T32 EB007507
6 · The paper itself

Abstract

Significance: Two-photon microscopy is widely used for Aim: We aim to investigate the feasibility of using liposomal nanoparticles that, when used to encapsulate ICG, significantly increase the circulation time of the vascular label in the rodent body. Approach: We conducted Results: In comparison to a retention time of around 20 min for free ICG, we find that liposomal encapsulation improves the vascular retention time of the dye to at least 75 min. The improvement in retention time using the encapsulation technique was consistent across imaging experiments conducted in five mice. Conclusion: The rapid clearance of ICG from the rodent body can be overcome using liposomal encapsulation, making prolonged

Indexed as

Indocyanine GreenLiposomesMicroscopy, Fluorescence, MultiphotonAnimalsFluorescent DyesMiceNanoparticlesFluorescent DyesIndocyanine GreenLiposomesindocyanine greenliposomal encapsulationtwo-photon microscopy

Identifiers

PMID40995533
PMCPMC12456867

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.