Evidence map›Paper›PMID 40995463›Full record

ArticleHemaSphere2025

Large B-cell lymphoma (LBCL): EHA Clinical Practice Guidelines for diagnosis, treatment, and follow-up.

Catherine Thieblemont, Maria Gomes Da Silva, Sirpa Leppä, Georg Lenz, Anne-Ségolène Cottereau, Christopher Fox, Armando Lopez-Guillermo, Timothy Illidge, Wojciech Jurczak, Hans Eich and 13 more

Erratum issuedAbstract read
In one paragraph

Article in HemaSphere, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
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  7. Article
  8. Article
  9. Review
  10. High-Dose Methotrexate as CNS Prophylaxis in Ultra High-Risk Large B-Cell Lymphoma: An International Multicenter Analysis.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2026
    Article
  11. Review
  12. Article
  13. Quality of Life in CAR-T Cell Therapy.Hematology reports · 2026
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors.

Catherine ThieblemontUniversité Paris Cité Paris France.
Maria Gomes Da SilvaHematology Department Instituto Portugues de Oncologia Lisbon Portugal.
Sirpa LeppäUniversity of Helsinki and Helsinki University Hospital Helsinki Finland.ORCID https://orcid.org/0000-0002-8265-511X
Georg LenzHematology & Oncology University Hospital Münster Münster Germany.
Anne-Ségolène CottereauAssistance Publique - Hôpitaux de Paris, Hôpital Cochin Université Paris Paris France.
Christopher FoxSchool of Medicine University of Nottingham Nottingham United Kingdom.
Armando Lopez-GuillermoHospital Clinic y Provincial de Barcelona Barcelona Spain.
Timothy IllidgeThe Christie NHS Foundation Trust, Manchester NIHR Biomedical Research Centre University of Manchester Manchester United Kingdom.
Wojciech JurczakMaria Skłodowska-Curie National Research Institute of Oncology Warszawa Poland.
Hans EichDepartment of Radiation Oncology University Hospital Muenster Münster Germany.
Igor AurerUniversity Hospital Centre Zagreb and School of Medicine, University of Zagreb Zagreb Croatia.
Marek TrnenyCharles University Prague Czech Republic.
Andy Andreas RosenwaldUniversity of Wuerzburg Würzburg Germany.
Andrew DaviesMedical Oncology Department, Southampton General Hospital University Hospital Southampton NHS Trust Southampton United Kingdom.
Ben Gerben ZwezerijnenAmsterdam UMC University Amsterdam The Netherlands.
Natacha BolanosLymphoma Coalition Mississauga ON Canada.
Maja MarkovićLymphoma Coalition Mississauga ON Canada.
Jean-Philippe JaisUniversité Paris Cité Paris France.
Florence BroussaisInstitut Carnot Calym Paris France.ORCID https://orcid.org/0009-0004-5841-5409
Martin DreylingDepartment of Medicine III LMU Munich Germany.
Umberto VitoloCandiolo Cancer Institute, FPO-IRCCS Turin Italy.
Hervé TillyDepartment of Hematology and INSERM U1245 Centre Henri Becquerel Rouen France.
Marie-José KerstenUniversitair Medische Centra Amsterdam Amsterdam The Netherlands.ORCID https://orcid.org/0000-0002-8904-3802

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Large B-cell lymphoma (LBCL) accounts for about one-third of adult lymphoma cases. Diagnosis requires specialized hematopathology laboratories, with immunophenotypic analysis essential for confirming B-cell lineage and identifying variants.

Identifiers

PMID40995463
PMCPMC12456099

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.