Evidence map›Paper›PMID 40995358›Full record

ArticleSynthesis2025

Unexpected Regiochemical Control in the Nugent-RajanBabu Reductive Epoxide Cyclization.

Nantamon Supantanapong, Scott W Niman, Christopher D Vanderwal

Abstract read
In one paragraph

Article in Synthesis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nantamon SupantanapongDepartment of Chemistry, 1102 Natural Sciences II, University of California, Irvine, CA 92697, USA.
Scott W NimanDepartment of Chemistry, 1102 Natural Sciences II, University of California, Irvine, CA 92697, USA.
Christopher D VanderwalDepartment of Chemistry, 1102 Natural Sciences II, University of California, Irvine, CA 92697, USA.

Funding

Chemical Synthesis of Bioactive DiterpenoidsR35GM145252 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI Christopher D Vanderwal · 2022 to 2026
$2.1M
NIGMS NIH HHS R35 GM145252
6 · The paper itself

Abstract

The Nugent-RajanBabu reductive epoxide cyclization has become a mainstay of alternative methods to accomplish classical, biomimetic, cationic polyene cyclizations. In most cases, the regiochemical control for the formation of decalins and perhydrophenanthrenes is exquisite, mirroring that obtained in cationic reactions, to the point where the 6-

Indexed as

cyclizationsepoxideradicalregiocontrolterpenoidstotal synthesis

Identifiers

PMID40995358
PMCPMC12456417

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.