Evidence map›Paper›PMID 40995307›Full record

ArticleCureus2025

Evaluation of Telomerase Reverse Transcriptase (TERT) Promoter Mutations in Photodynamic Diagnosis With 5-Aminolevulinic Acid False-Positive Sites in Non-muscle-Invasive Bladder Cancer.

Yoshitaka Saito, Shogo Adomi, Kazuko Sakai, Marco Antonio De Velasco, Mamoru Hashimoto, Eri Banno, Yujiro Hayashi, Takafumi Minami, Kazuto Nishio, Kazutoshi Fujita

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yoshitaka SaitoUrology, Kindai University Hospital, Osakasayama, JPN.
Shogo AdomiUrology, Kindai University Hospital, Osakasayama, JPN.
Kazuko SakaiGenome Biology, Kindai University Hospital, Osakasayama, JPN.
Marco Antonio De VelascoGenome Biology, Kindai University Hospital, Osakasayama, JPN.
Mamoru HashimotoUrology, Kindai University Hospital, Osakasayama, JPN.
Eri BannoUrology, Mimihara General Hospital, Sakai, JPN.
Yujiro HayashiUrology, Johns Hopkins University, Baltimore, USA.
Takafumi MinamiUrology, Kindai University Hospital, Osakasayama, JPN.
Kazuto NishioGenome Biology, Kindai University Hospital, Osakasayama, JPN.
Kazutoshi FujitaUrology, Kindai University Hospital, Osakasayama, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimPhotodynamic diagnosis (PDD) with 5-aminolevulinic acid (5-ALA) can be used to detect bladder cancer lesions, but false-positive results without pathological malignancy could sometimes occur. However, a false-positive lesion might be the precancerous lesion. Telomerase reverse transcriptase ( MATERIALS AND

methodsAmong 117 patients who underwent PDD-TURBT for NMIBC, 18 NMIBC patients who had PDD with 5-ALA positive samples, which were pathologically diagnosed as no malignant diseases, were included in this study.

results

conclusions

Indexed as

5-aminolevulinic acidbladder cancerphotodynamic diagnosistert promoter mutationturbt

Identifiers

PMID40995307
PMCPMC12455374

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.