Evidence map›Paper›PMID 40995291›Full record

ReviewCureus2025

Efficacy of Dietary Interventions in Managing Irritable Bowel Syndrome: A Systematic Review of Clinical Outcomes and Gut Microbiota Modulation.

Hassan Ghega, Zulfiqar Ali, Saad Sohail, Shivam Singla, Bhavna Singla, Zeeshan Kamal, Sunita Kumawat, Simran Kumari, Komal Sohail, Nabila N Anika and 1 more

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hassan GhegaInternal Medicine, District Headquarters Teaching Hospital, Gujranwala, PAK.
Zulfiqar AliInternal Medicine, Chandka Medical College, Larkana, PAK.
Saad SohailInternal Medicine, Mayo Hospital, Lahore, PAK.
Shivam SinglaInternal Medicine, TidalHealth Peninsula Regional, Salisbury, USA.
Bhavna SinglaInternal Medicine, Erie County Medical Center (ECMC) Hospital, Buffalo, USA.
Zeeshan KamalInternal Medicine, King Edward Medical University, Lahore, PAK.
Sunita KumawatInternal Medicine, Hackensack Meridian Ocean University Medical Center, Brick, USA.
Simran KumariInternal Medicine, Chandka Medical College, Larkana, PAK.
Komal SohailInternal Medicine, Sahiwal Medical College, Sahiwal, PAK.
Nabila N AnikaGeneral Surgery, University of South Florida Health, Florida, USA.
Muhammad Usman FareedGeneral Surgery, Nishtar Medical University, Multan, PAK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This systematic review explores the effectiveness of dietary interventions in the management of irritable bowel syndrome (IBS), focusing on clinical outcomes and gut microbiota modulation. A broad search of medical literature identified several high-quality studies examining dietary approaches such as low fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP) diets, gluten-free regimens, and fiber supplementation. Across the included studies, these interventions were consistently associated with reductions in symptom severity and improvements in quality of life (QOL). In addition, several dietary strategies contributed to favorable changes in gut microbial composition, supporting the role of diet in influencing underlying mechanisms of IBS. Tailored interventions that accounted for individual food sensitivities or triggers demonstrated greater clinical benefit and adherence. Overall, the findings emphasize the potential of personalized dietary modifications as a cornerstone of IBS management. However, further investigation is needed to evaluate long-term outcomes, sustainability, and cost-effectiveness of these approaches across varied patient populations.

Indexed as

dietary interventionsgut microbiotairritable bowel syndromelow fodmap dietpersonalized nutritionquality of lifesystematic review

Identifiers

PMID40995291
PMCPMC12456667

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.