ArticleCureus2025
Vein Transillumination Versus the Standard Method in Neonatal Venous Cannulation: A Randomized Trial.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPeripheral venous cannulation is an essential procedure in neonatal intensive care units (NICUs) but is often associated with high failure rates. Near-infrared vein visualization devices may enhance vein identification and reduce the number of attempts; however, evidence in neonatal populations remains limited. This study aimed to compare the first-attempt success rates of peripheral venous cannulation using a vein transillumination device versus the standard method in neonates with prior punctures. Secondary analyses explored patient- and performer-related factors associated with successful cannulation. Methodology: This study conducted a prospective, randomized controlled trial from October 2022 to January 2024 in the NICU at Hospital Sultan Abdul Aziz Shah, Universiti Putra Malaysia. Only neonates of ≥ 35 weeks of gestation requiring venous access with at least one prior venipuncture were enrolled. The participants were randomized into standard (control) and AccuVein AV500-assisted (intervention) cannulation groups. All procedures were performed by 14 trained medical officers. First-attempt success was documented as the primary outcome, while secondary outcomes included associations with patient, performer, and procedural factors.
resultsA total of 120 neonates were enrolled (60 per group). The overall first-attempt peripheral venous cannulation success rate was 47 (39.2%). No significant differences were observed between the control (21, 35%) and the intervention (26, 43.3%) groups (
conclusionsVein transillumination did not significantly improve the first-attempt peripheral venous cannulation success rate. However, vein palpability, fewer prior punctures, and right-sided cannulation were associated with superior outcomes.
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